We are exploring novel vaccines and therapies to eradicate cancers.
Jefferson Center for Vaccines & Pandemic Preparedness Research
Contact
Position:
Chair & Professor, SKMC Department of Microbiology & Immunology
233 South Tenth Street
Bluemle Life Sciences Building, 531
Philadelphia, PA 19107
Contact Number(s):
Name:
Christopher M. Snyder, PhD
Position:
Associate Director for Basic Research
Name:
Christopher Chambers, MD
Position:
Associate Director for Clinical Research
Center Information
Name:
Cheryl King-Marino
Position:
JCVPP Administrator
Email:
Cheryl.King@jefferson.edu
Cancer Vaccines & Cancer Immunogenicity
Faculty Research/Lab Sites & Publications
Names are linked to their respective lab web sites or academic profiles.
Sangwon Kim, PhD
Associate Professor, Department of Microbiology & Immunology
Publications
- C10ORF99 (GPR15L) increases susceptibility to colitis and colitis-induced colorectal cancer via GPR15-independent mechanisms, while mediating GPR15-dependent T cell migration to the large intestine
- Author Correction: GPR15-mediated T cell recruitment during acute viral myocarditis facilitated virus elimination and improved outcome(Nature Cardiovascular Research, 10.1038/s44161-023-00401-z)
- GPR15-mediated T cell recruitment during acute viral myocarditis facilitated virus elimination and improved outcome
- Dietary L-Tryptophan consumption determines the number of colonic regulatory T cells and susceptibility to colitis via GPR15
- Enforced gut homing of murine regulatory T cells reduces early graft-versus-host disease severity
Felix Kim, PhD
Professor, Department of Microbiology & Immunology
Publications
- Unplanned hospitalization among advanced prostate cancer patients by diabetes status: A population-based study
- Sigma1 inhibitor suppression of adaptive immune resistance mechanisms mediated by cancer cell derived extracellular vesicles
- A student-community partnership to enhance cancer research training
- Prostein expression on circulating tumor cells as a prognostic marker in metastatic castration-resistant prostate cancer
- Sigma1 Regulates Lipid Droplet-Mediated Redox Homeostasis Required for Prostate Cancer Proliferation
Adam Snook, PhD
Associate Professor, Department of Microbiology & Immunology
Publications
- Could GUCY2C-targeted pharmacotherapy be effective in treating colorectal cancer?
- IFNγ-induced antigen loss in chimeric antigen receptor-T cell therapy
- Cancer Vaccination and Immune-Based Approaches in Pancreatic Cancer
- Immunotherapy for precision medicine in colorectal cancer
- GUCY2C signaling limits dopaminergic neuron vulnerability to toxic insults
Yuri Sykulev, MD, PhD
Professor, Department of Microbiology & Immunology
Publications
- The role of peptide conformation presented by MHC in the induction of TCR triggering
- The FcγRIIIA (CD16) L48-H/R Polymorphism Enhances NK Cell–Mediated Antibody-Dependent Cellular Cytotoxicity by Promoting Serial Killing
- Factors contributing to the potency of CD8+ T cells
- The immune synapses reveal aberrant functions of CD8 T cells during chronic HIV infection
- Efficient killing of tumor cells by CAR-T cells requires greater number of engaged CARs than TCRs