Jefferson Center for Vaccines & Pandemic Preparedness Research
Contact
Position:
Chair & Professor, SKMC Department of Microbiology & Immunology
233 South Tenth Street
Bluemle Life Sciences Building, 531
Philadelphia, PA 19107
Contact Number(s):
Position:
Associate Director for Basic Research
Position:
Associate Director for Clinical Research
Center Information
Position:
JCVPP Administrator
Email:
Cheryl.King@jefferson.edu
Cancer Vaccines & Cancer Immunogenicity
We are exploring novel vaccines and therapies to eradicate cancers.
Faculty Research/Lab Sites & Publications
Names are linked to their respective lab web sites or academic profiles.
Sangwon Kim, PhD
Associate Professor, Department of Microbiology & Immunology
Publications
- Author Correction: GPR15-mediated T cell recruitment during acute viral myocarditis facilitated virus elimination and improved outcome(Nature Cardiovascular Research, 10.1038/s44161-023-00401-z)
- GPR15-mediated T cell recruitment during acute viral myocarditis facilitated virus elimination and improved outcome
- Dietary L-Tryptophan consumption determines the number of colonic regulatory T cells and susceptibility to colitis via GPR15
- Enforced gut homing of murine regulatory T cells reduces early graft-versus-host disease severity
- Improved approach for the cryopreservation of mouse sperm by combining monothioglycerol and L-glutamine
Felix Kim, PhD
Professor, Department of Microbiology & Immunology
Publications
- Prostein expression on circulating tumor cells as a prognostic marker in metastatic castration-resistant prostate cancer
- Sigma1 Regulates Lipid Droplet-Mediated Redox Homeostasis Required for Prostate Cancer Proliferation
- Review of Cardiovascular Risk of Androgen Deprivation Therapy and the Influence of Race in Men with Prostate Cancer
- Haloperidol and Prostate Cancer Prevention: More Epidemiologic Research Needed
- Small-molecule modulators of sigma1 and SiGma2/TMEM97 in the context of cancer: Foundational concepts and emerging themes
Adam Snook, PhD
Associate Professor, Department of Microbiology & Immunology
Publications
- GUCY2C signaling limits dopaminergic neuron vulnerability to toxic insults
- Biomarkers for Managing Neurodegenerative Diseases
- CD8α Structural Domains Enhance GUCY2C CAR-T Cell Efficacy
- CD5 deletion enhances the antitumor activity of adoptive T cell therapies
- In vitro assays to evaluate CAR-T cell cytotoxicity
Yuri Sykulev, MD, PhD
Professor, Department of Microbiology & Immunology
Publications
- Factors contributing to the potency of CD8+ T cells
- The immune synapses reveal aberrant functions of CD8 T cells during chronic HIV infection
- Efficient killing of tumor cells by CAR-T cells requires greater number of engaged CARs than TCRs
- The DISC1–Girdin complex – a missing link in signaling to the T cell cytoskeleton
- Protective Allele for Multiple Sclerosis HLA-DRB1*01:01 Provides Kinetic Discrimination of Myelin and Exogenous Antigenic Peptides