Clinical trials at Jefferson are testing some of the latest approaches to defeating infectious diseases.
Jefferson Center for Vaccines & Pandemic Preparedness Research
Contact
Position:
Chair & Professor, SKMC Department of Microbiology & Immunology
233 South Tenth Street
Bluemle Life Sciences Building, 531
Philadelphia, PA 19107
Contact Number(s):
Name:
Christopher M. Snyder, PhD
Position:
Associate Director for Basic Research
Name:
Christopher Chambers, MD
Position:
Associate Director for Clinical Research
Center Information
Name:
Cheryl King-Marino
Position:
JCVPP Administrator
Email:
Cheryl.King@jefferson.edu
Clinical Research
Faculty Research/Lab Sites & Publications
Names are linked to their respective lab web sites or academic profiles.
Sara Boudova, MD
Maternal-Fetal Medicine Fellow, Department of Obstetrics & Gynecology
Sara Boudova, MD
Maternal-Fetal Medicine Fellow, Department of Obstetrics & Gynecology
Publications
- Increasing dialogue surrounding controversies in antepartum management among trainees
- Increasing dialogue surrounding controversies in antepartum management among trainees
- Invited Perspective: Climate Change and Maternal Mental Health—Looking beyond High-Income Countries
- Hepatitis C virus detection and management after implementation of universal screening in pregnancy
- Bacterial and Parasitic Infections in Pregnancy
Christopher Chambers, MD
Professor, Department of Family & Community Medicine
Director, Clinical Trials
Christopher Chambers, MD
Professor, Department of Family & Community Medicine
Director, Clinical Trials
Publications
- COVID-19 mRNA Vaccination Trends Among Immunocompromised Patients
- Primary care patient interests in joining a planned multi-cancer early detection clinical trial
- Primary Care Provider Receptivity to Multi-Cancer Early Detection Test Use in Cancer Screening
- Primary Care Patient Interest in Multi-Cancer Early Detection for Cancer Screening
- Primary care provider perspectives on a planned multi-cancer early detection test clinical trial
Walter Kraft, MD
Professor, Department of Pharmacololgy, Physicology & Cancer Biology
Director, Clinical Research Unit
Director, Office of Human Research Protection
Publications
- Optimal Drug, Optimal Dose, or Both in the Pharmacological Treatment of Neonatal Opioid Withdrawal Syndrome?
- Pharmacodynamics of Aspirin Through Gestation: Predictors of Aspirin Response and Association With Pregnancy Outcome, a Prospective Cohort Study
- Bayesian Population Pharmacokinetic Modeling of Ondansetron for Neonatal Opioid Withdrawal Syndrome
- The role of 5-HT modulation in opioid withdrawal and neonatal opioid withdrawal syndrome: mechanisms and potential serotonergic targets
- Assessment of pharmacokinetics and tolerability following single-dose administration of molnupiravir in participants with hepatic or renal impairment
Matthias Schnell, PhD
Chair, Department of Microbiology & Immunology
Dr. V. Watson Pugh & Frances Plimpton Pugh Professor in Microbiology & Immunology
Director, Jefferson Center for Vaccines & Pandemic Preparedness
Publications
- Inactivated rabies-based Lassa fever virus vaccine candidate LASSARAB protects nonhuman primates from lethal disease
- Toward the Development of a Pan-Lyssavirus Vaccine
- The Development of a Rabies Virus-Vectored Vaccine against Borrelia burgdorferi, Targeting BBI39
- GP38 as a vaccine target for Crimean-Congo hemorrhagic fever virus
- Effects of adjuvants in a rabies-vectored Ebola virus vaccine on protection from surrogate challenge
Yuri Sykulev, MD, PhD
Professor, Department of Microbiology & Immunology
Publications
- The role of peptide conformation presented by MHC in the induction of TCR triggering
- The FcγRIIIA (CD16) L48-H/R Polymorphism Enhances NK Cell-Mediated Antibody-Dependent Cellular Cytotoxicity by Promoting Serial Killing
- Factors contributing to the potency of CD8+ T cells
- The immune synapses reveal aberrant functions of CD8 T cells during chronic HIV infection
- Efficient killing of tumor cells by CAR-T cells requires greater number of engaged CARs than TCRs