Clinical trials at Jefferson are testing some of the latest approaches to defeating infectious diseases.
Jefferson Center for Vaccines & Pandemic Preparedness Research
Contact
Position:
Chair & Professor, SKMC Department of Microbiology & Immunology
233 South Tenth Street
Bluemle Life Sciences Building, 531
Philadelphia, PA 19107
Contact Number(s):
Name:
Christopher M. Snyder, PhD
Position:
Associate Director for Basic Research
Name:
Christopher Chambers, MD
Position:
Associate Director for Clinical Research
Center Information
Name:
Cheryl King-Marino
Position:
JCVPP Administrator
Email:
Cheryl.King@jefferson.edu
Clinical Research
Faculty Research/Lab Sites & Publications
Names are linked to their respective lab web sites or academic profiles.
Sara Boudova, MD
Maternal-Fetal Medicine Fellow, Department of Obstetrics & Gynecology
Publications
- Safety and Effectiveness of Uterine Gauze Packing for Refractory Postpartum Haemorrhage: A Systematic Review and Meta-Analysis
- Cervical dilation staging and early preterm birth risk after examination–indicated cerclage: a retrospective cohort study with the International Collaborative for Cerclage Longitudinal Evaluation and Research
- Spectrum of congenital anomalies detected through anatomy ultrasound at a referral hospital in Ghana
- The Relationship between Placental Malaria and Preeclampsia in Blantyre, Malawi
- The Effect of HCV on Methadone Dose During Pregnancy
Christopher Chambers, MD
Professor, Department of Family & Community Medicine
Director, Clinical Trials
Publications
- Implementation of the Person-Centered Primary Care Measure
- Multi-cancer early detection tests: Attributes for clinical implementation
- COVID-19 mRNA Vaccination Trends Among Immunocompromised Patients
- Primary care patient interests in joining a planned multi-cancer early detection clinical trial
- Primary Care Provider Receptivity to Multi-Cancer Early Detection Test Use in Cancer Screening
Walter Kraft, MD
Professor, Department of Pharmacololgy, Physicology & Cancer Biology
Director, Clinical Research Unit
Director, Office of Human Research Protection
Publications
- Platelet-Associated microRNAs as Markers of Aspirin Response and Pregnancy Outcome in Pregnancies at High-Risk for Preeclampsia
- Azithromycin in preterm premature rupture of membranes: population pharmacokinetics and dose optimization
- Hydroxypropyl Methylcellulose as a Mucoadhesive Polymer in Ethanol-Free Buprenorphine Gel for Neonatal Sublingual Delivery
- GLP-1s Versus DPP-4s and Risk of Dementia in Patients Requiring Hemodialysis: A Target Trial Emulation Study
- Optimizing pharmacologic treatment for neonatal opioid withdrawal syndrome (OPTimize NOW): a symptom-based dosing approach study protocol for a multi-center, cluster crossover design randomized controlled trial
Matthias Schnell, PhD
Chair, Department of Microbiology & Immunology
Dr. V. Watson Pugh & Frances Plimpton Pugh Professor in Microbiology & Immunology
Director, Jefferson Center for Vaccines & Pandemic Preparedness
Publications
- Immunogenicity and efficacy of a rabies-based vaccine against highly pathogenic influenza H5N1 virus
- Rabies virus-vectored Lyme disease vaccine provides long-term protection against tick-transmitted Borrelia burgdorferi
- Immunogenicity and safety of a rabies-based highly pathogenic influenza A virus H5 vaccine in cattle
- Inactivated rabies-based Lassa fever virus vaccine candidate LASSARAB protects nonhuman primates from lethal disease
- Toward the Development of a Pan-Lyssavirus Vaccine
Yuri Sykulev, MD, PhD
Professor, Department of Microbiology & Immunology
Publications
- The role of peptide conformation presented by MHC in the induction of TCR triggering
- The FcγRIIIA (CD16) L48-H/R Polymorphism Enhances NK Cell–Mediated Antibody-Dependent Cellular Cytotoxicity by Promoting Serial Killing
- Factors contributing to the potency of CD8+ T cells
- The immune synapses reveal aberrant functions of CD8 T cells during chronic HIV infection
- Efficient killing of tumor cells by CAR-T cells requires greater number of engaged CARs than TCRs