Jefferson Center for Vaccines & Pandemic Preparedness Research
Contact
233 South Tenth Street
Bluemle Life Sciences Building, 531
Philadelphia, PA 19107
Center Information
Clinical Research
Clinical trials at Jefferson are testing some of the latest approaches to defeating infectious diseases.
Faculty Research/Lab Sites & Publications
Names are linked to their respective lab web sites or academic profiles.
Sara Boudova, MD
Maternal-Fetal Medicine Fellow, Department of Obstetrics & Gynecology
Sara Boudova, MD
Maternal-Fetal Medicine Fellow, Department of Obstetrics & Gynecology
Publications
- Invited Perspective: Climate Change and Maternal Mental Health—Looking beyond High-Income Countries
- Hepatitis C virus detection and management after implementation of universal screening in pregnancy
- Pregnancy as an Opportunity for Hepatitis C Virus Elimination and Eradication
- Concomitant assessment of PD-1 and CD56 expression identifies subsets of resting cord blood Vδ2 T cells with disparate cytotoxic potential
- Percutaneous debulking of tricuspid vegetations due to infectious endocarditis in pregnancy: a case report
Christopher Chambers, MD
Professor, Department of Family & Community Medicine
Director, Clinical Trials
Christopher Chambers, MD
Professor, Department of Family & Community Medicine
Director, Clinical Trials
Publications
- COVID-19 mRNA Vaccination Trends Among Immunocompromised Patients
- Primary care patient interests in joining a planned multi-cancer early detection clinical trial
- Primary Care Provider Receptivity to Multi-Cancer Early Detection Test Use in Cancer Screening
- Primary Care Patient Interest in Multi-Cancer Early Detection for Cancer Screening
- Primary care provider perspectives on a planned multi-cancer early detection test clinical trial
Walter Kraft, MD
Professor, Department of Pharmacololgy, Physicology & Cancer Biology
Director, Clinical Research Unit
Director, Office of Human Research Protection
Publications
- Assessment of pharmacokinetics and tolerability following single-dose administration of molnupiravir in participants with hepatic or renal impairment
- Macrophage uptake rate of Sonazoid in breast lymphosonography is highly conserved in healthy controls
- Intracellular islatravir-triphosphate half-life supports extended dosing intervals
- Azithromycin dosing and preterm premature rupture of membranes treatment (ADAPT): a randomized controlled Phase I trial
- Aspirin pharmacokinetics and pharmacodynamics through gestation
Matthias Schnell, PhD
Chair, Department of Microbiology & Immunology
Dr. V. Watson Pugh & Frances Plimpton Pugh Professor in Microbiology & Immunology
Director, Jefferson Center for Vaccines & Pandemic Preparedness
Publications
- Inactivated rabies-based Lassa fever virus vaccine candidate LASSARAB protects nonhuman primates from lethal disease
- Toward the Development of a Pan-Lyssavirus Vaccine
- The Development of a Rabies Virus-Vectored Vaccine against Borrelia burgdorferi, Targeting BBI39
- GP38 as a vaccine target for Crimean-Congo hemorrhagic fever virus
- Effects of adjuvants in a rabies-vectored Ebola virus vaccine on protection from surrogate challenge
Yuri Sykulev, MD, PhD
Professor, Department of Microbiology & Immunology
Publications
- Factors contributing to the potency of CD8+ T cells
- The immune synapses reveal aberrant functions of CD8 T cells during chronic HIV infection
- Efficient killing of tumor cells by CAR-T cells requires greater number of engaged CARs than TCRs
- The DISC1–Girdin complex – a missing link in signaling to the T cell cytoskeleton
- Protective Allele for Multiple Sclerosis HLA-DRB1*01:01 Provides Kinetic Discrimination of Myelin and Exogenous Antigenic Peptides