The goal of the Sidney Kimmel Cancer Center Bioimaging Shared Resource is to advance the scientific research programs of the Cancer Center by providing SKCC investigators powerful, reliable, and readily accessible light microscopy.  The Bioimaging Shared Resource provides a state of the art STED (stimulated emission depletion) super-resolution system, galvo and resonnat laser point-scanning confocals, spinning disk confocal, and TIRF (total internal refection fluorescence) modalities.  The staff provides in-house training on all instruments.

Fluorescence microscopy requires the use of intense illumination at specific wavelengths, traditionally in the visible spectrum.  For decades, this illumination relied on mercury based lamps, which had relatively short lifespans and unreliable intensities.  With the introduction of LED-based light sources, fluorescence research no longer needs to rely on these outdated, costly, and environmentally hazardous mercury sources.  The BISF is seeking to remove and replace all mercury sources on campus with their LED counterparts, but it starts with knowing more about the mercury footprint at Jefferson.  If your lab works with fluorescent microsopes, please fill out the survey below.

Light microscopy has changed the way data are collected, from the early days of modeln visualization and illustration to database mining massive data sets for trends.  The inherent data within these images is extracted, measured, and comapred through quantitative image analysis.  This is an aspect to modern microscopy that we at the BISF would like grow in our offerings.  To help us learn about your lab's analysis methods and needs, please fill out the survey below.

Effective presentation of microscopy data is critical part of digital imaing.  The BioImaging Shared Resource would like to explore this in an informal journal club.  To learn more and be added to our email list, please fill out the survey below.