Rahman Research
CONTACT
233 S. 10th Street
BLSB 731
Philadelphia, PA 19107
Highlighted Publications
Fike AJ, Chodisetti SB, Wright NE, Bricker KN, Domeier PP, Maienschein-Cline M, Rosenfeld AM, Luckenbill SA, Weber JL, Choi NM, Luning Prak ET, Mandal M, Clark MR, Rahman ZS. STAT3 signaling in B cells controls germinal center zone organization and recycling. Cell Rep. 2023 May 30;42(5):112512. PMID: 37200190.
Domeier PD, Chodisetti SB, Soni C*, Schell SL, Elias MJ, Wong EB, Cooper T, Kitamura D, and Rahman ZS. Interferon-γ receptor and STAT1 signaling in B cells are central to spontaneous germinal center formation and autoimmunity. J. Exp. Med, e-published ahead of print, April 11, 2016, doi:10.1084/jem.20151722. PMCID: PMC4854731 (* Equal second authorship).
Domeier PP, Chodisetti SB, Schell SL, Kawasawa YI, Fasnacht MJ, Soni C, Rahman ZSM. B-Cell-Intrinsic Type 1 Interferon Signaling Is Crucial for Loss of Tolerance and the Development of Autoreactive B Cells. Cell Rep. 2018 Jul 10; 24(2):406-418. PMCID: PMC6089613.
Schell SL, Bricker KN, Fike AJ, Chodisetti SB, Domeier PP, Choi NM, Fasnacht MJ, Sara A. Luckenbill SA, Ziegler SF, and Rahman ZS. Context-dependent miR-21 regulation of TLR7-mediated autoimmune and foreign antigen driven antibody-forming cell and germinal center responses. J Immunol. 2021 May 26:ji2001039. doi: 10.4049/jimmunol.2001039. PMID: 34039637.
Publications
- STAT3 signaling in B cells controls germinal center zone organization and recycling
- Orai3 and Orai1 mediate CRAC channel function and metabolic reprogramming in B cells
- B cell– and T cell–intrinsic regulation of germinal centers by thymic stromal lymphopoietin signaling
- The mitochondrial sodium/calcium exchanger NCLX (Slc8b1) in B lymphocytes
- Regulation of B cell responses in sle by three classes of interferons
- The cyclin-dependent kinase 8 (CDK8) inhibitor DCA promotes a tolerogenic chemical immunophenotype in CD4+ T cells via a novel CDK8-GATA3-FOXP3 pathway
- New developments implicating IL-21 in autoimmune disease
- Context-dependent mir-21 regulation of tlr7-mediated autoimmune and foreign antigen-driven antibody-forming cell and germinal center responses
- miRNA-Mediated Control of B Cell Responses in Immunity and SLE
- STAT4 Is Largely Dispensable for Systemic Lupus Erythematosus–like Autoimmune- And Foreign Antigen–Driven Antibody-Forming Cell, Germinal Center, and Follicular Th Cell Responses
- IL-21 from high-affinity CD4 T cells drives differentiation of brain-resident CD8 T cells during persistent viral infection
- TLR7 Negatively Regulates B10 Cells Predominantly in an IFNγ Signaling Dependent Manner
- Serine phosphorylation of the STAT1 transactivation domain promotes autoreactive B cell and systemic autoimmunity development
- Type II but not type I IFN signaling is indispensable for TLR7-promoted development of autoreactive B cells and systemic autoimmunity
- Crispr-cas replacing antiviral drugs against hiv: An update
- Gut-resident CX3CR1hi macrophages induce tertiary lymphoid structures and IgA response in situ
- Strain-Dependent Contribution of MAVS to Spontaneous Germinal Center Responses
- Selenium supplementation suppresses immunological and serological features of lupus in B6.Sle1b mice
- The Post-GWAS Era: How to Validate the Contribution of Gene Variants in Lupus
- B-Cell-Intrinsic Type 1 Interferon Signaling Is Crucial for Loss of Tolerance and the Development of Autoreactive B Cells