Contact
233 South 10th Street
833 BLSB
Philadelphia, PA 19107
Highlighted Publications
De Pascali, F., Ippolito, M., Wolfe, E., Komolov, K. E., Hopfinger, N., Lemenze, D., Kim, N., Armen, R. S., Am, S. S., Scott, C. P., Benovic, J. L. "Beta-2-Adrenoreceptor agonist profiling reveals biased signalling phenotypes for the beta-2-adrenoreceptor with possible implications for the treatment of asthma." British J. Pharmacol. (2022) 1-17. PMC9474705
Yano, T., Rahimian, M., Aneja, K., Schechter, N., Rubin, H., Scott, C. P. “Mycobacterium tuberculosis type II NADH-Menaquinone oxidoreductase (NDH-2) catalyzes electron transfer through a two-site ping-pong mechanism and has two quinone binding sites." Biochemistry 57 (7), 1179 – 90 (2014). PMC3985514
Xiong, L., Scott, C. P. (2014) “Bioprospecting open reading frames for peptide effectors” Methods in Molecular Biology 1088: 81 – 96 (2014). PMID: 24148398
Juliana, C., Fernandez-Alnemri, T., Wu, J., Datta, P., Solorzano, L., Yu, J-W., Meng, R., Quong, A. A., Latz, E., Scott, C. P., Alnemri, E. S. “Anti-inflammatory compounds parthenolide and Bay 11-7082 are direct inhibitors of the inflammasome.” J. Biol. Chem. 285 (13), 9792 – 802 (2010). PMC2843228
Scott, C. P., Abel-Santos, E., Wall, M., Wahnon, D. C., Benkovic, S. J. (1999) "The production of cyclic peptides and proteins in vivo." Proceedings of the National Academy of Sciences (USA) 96 (24), 13638-43. PMC24117
Publications
- Identification of a β-arrestin-biased negative allosteric modulator for the β2-adrenergic receptor
- β2-Adrenoceptor agonist profiling reveals biased signalling phenotypes for the β2-adrenoceptor with possible implications for the treatment of asthma
- Mycobacterium tuberculosis type II NADH-menaquinone oxidoreductase catalyzes electron transfer through a two-site ping-pong mechanism and has two quinone-binding sites
- Bioprospecting open reading frames for peptide effectors
- Anti-inflammatory compounds parthenolide and bay 11-7082 are direct inhibitors of the inflammasome
- Taking the chemical out of chemical genetics
- Effect of rapamycin on mouse chronic lymphocytic leukemia and the development of nonhematopoietic malignancies in Eμ-TCL1 transgenic mice
- Use of inteins for the in vivo production of stable cyclic peptide libraries in E. coli.
- A comprehensive model for the allosteric regulation of mammalian ribonucleotide reductase. Functional consequences of ATP- and dATP-induced oligomerization of the large subunit
- Structural requirements for the biosynthesis of backbone cyclic peptide libraries
- A quantitative model for allosteric control of purine reduction by murine ribonucleotide reductase
- Production of cyclic peptides and proteins in vivo
- High level expression of the large subunit of mouse ribonucleotide reductase in a baculovirus system