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McKenzie Research

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Steven McKenzie, MD, PhD
  • Leandro M. Tocantins, MD - Farid I. Haurani, MD Director, Cardeza Foundation for Hematologic Research
  • Director, Hereditary Anemias Program
  • Associate Director, Hemophilia Center
  • Professor of Medicine
Department of Medicine, Division of Hematology

Recent Publications

Antithrombotic efficacy and bleeding risks of vaccine-induced immune thrombotic thrombocytopenia treatments

Aspirin pharmacokinetics and pharmacodynamics through gestation

A mouse model of the protease-activated receptor 4 Pro310Leu variant has reduced platelet reactivity

Plasma growth factors maintain constitutive translation in platelets to regulate reactivity and thrombotic potential

Diagnostic value of antibody-induced procoagulant platelets in heparin-induced thrombocytopenia: communication from the ISTH SSC Subcommittee on Platelet Immunology

Phosphatidylserine-blocking nanoparticles inhibit thrombosis without increased bleeding in mice

The Function of ASK1 in Sepsis and Stress-Induced Disorders

Activation of coagulation and proinflammatory pathways in thrombosis with thrombocytopenia syndrome and following COVID-19 vaccination

Novel Strategy to Combat the Procoagulant Phenotype in Heparin-Induced Thrombocytopenia Using 12-LOX Inhibition

The predominant PAR4 variant in individuals of African ancestry worsens murine and human stroke outcomes

Species Differences in Platelet Protease-Activated Receptors

Characteristics of VITT antibodies in patients vaccinated with Ad26.COV2.S

Perioperative Outcomes of Patients with Bleeding Disorders Undergoing Major Surgery at an Academic Hemophilia Treatment Center

A vision for a quicker definitive diagnosis of HIT

Platelet protease activated receptor 4 (PAR 4) receptor genotype is associated with an increased risk of preterm birth

GRK2 regulates ADP signaling in platelets via P2Y1 and P2Y12

Human and mouse PAR4 are functionally distinct receptors: Studies in novel humanized mice

G protein–coupled receptor kinase 5 regulates thrombin signaling in platelets via PAR-1

Inhibition of NADPH oxidase blocks NETosis and reduces thrombosis in heparin-induced thrombocytopenia

Sugar and spike: not so nice

The SSC platelet immunology register of VITT and VIITP: Toward standardization of laboratory and clinical parameters

Coagulopathy monitoring and anticoagulation management in COVID-19 patients on ECMO: Advantages of a heparin anti-Xa-based titration strategy

Recommendations for the clinical and laboratory diagnosis of VITT against COVID-19: Communication from the ISTH SSC Subcommittee on Platelet Immunology

PCTP contributes to human platelet activation by enhancing dense granule secretion

Platelet FcγRIIA in immunity and thrombosis: Adaptive immunothrombosis

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