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Research
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McKenzie Research

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Steven McKenzie, MD, PhD
  • Professor of Medicine
  • Cardeza Foundation for Hematologic Research

Recent Publications

VLX-1005, but not argatroban, prevents ITAM-mediated platelet activation and heparin-induced thrombocytopenia

Understanding how a highly prevalent GRK5 polymorphism affects platelets and enhances thrombotic risk

Platelet-Associated microRNAs as Markers of Aspirin Response and Pregnancy Outcome in Pregnancies at High-Risk for Preeclampsia

Heparin-induced thrombocytopenia immune complexes activate the inflammasome pathway in a complement-dependent manner

Platelet defects in patients and mice with Ehlers-Danlos syndrome

Platelet protease-activated receptor 4 genotype and response to aspirin in pregnancy

Pharmacodynamics of Aspirin Through Gestation: Predictors of Aspirin Response and Association With Pregnancy Outcome, a Prospective Cohort Study

Phosphatidylserine-blocking nanoparticles inhibit thrombosis without increased bleeding in mice

Antithrombotic efficacy and bleeding risks of vaccine-induced immune thrombotic thrombocytopenia treatments

Aspirin pharmacokinetics and pharmacodynamics through gestation

A mouse model of the protease-activated receptor 4 Pro310Leu variant has reduced platelet reactivity

Plasma growth factors maintain constitutive translation in platelets to regulate reactivity and thrombotic potential

Diagnostic value of antibody-induced procoagulant platelets in heparin-induced thrombocytopenia: communication from the ISTH SSC Subcommittee on Platelet Immunology

The Function of ASK1 in Sepsis and Stress-Induced Disorders

Activation of coagulation and proinflammatory pathways in thrombosis with thrombocytopenia syndrome and following COVID-19 vaccination

Novel Strategy to Combat the Procoagulant Phenotype in Heparin-Induced Thrombocytopenia Using 12-LOX Inhibition

The predominant PAR4 variant in individuals of African ancestry worsens murine and human stroke outcomes

Species Differences in Platelet Protease-Activated Receptors

Characteristics of VITT antibodies in patients vaccinated with Ad26.COV2.S

Perioperative Outcomes of Patients with Bleeding Disorders Undergoing Major Surgery at an Academic Hemophilia Treatment Center

A vision for a quicker definitive diagnosis of HIT

Platelet protease activated receptor 4 (PAR 4) receptor genotype is associated with an increased risk of preterm birth

GRK2 regulates ADP signaling in platelets via P2Y1 and P2Y12

Human and mouse PAR4 are functionally distinct receptors: Studies in novel humanized mice

G protein–coupled receptor kinase 5 regulates thrombin signaling in platelets via PAR-1

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