Hou Research

Thomas Christian
Post-Doctoral Fellow

Research Project: I am interested in understanding the molecular and structural mechanisms of tRNA methyltransferases. I would like to determine how specific methyltransferases recognize their tRNA targets and to explore strategies that these enzymes catalyze methyl transfer.

Isao Masuda
Post-Doctoral Fellow

Research Project: I am interested in the mechanism of translational frameshifting, a non-standard phenomenon in decoding genetic codes into proteins. I am going to examine how the tRNAs and ribosomes are involved in frameshifting using both molecular biological and biochemical.

Kevin Donaldson
Masters Student

Research Project: I am interested in how pathogenic mutations in aminoacyl-tRNA synthetases are associated with peripheral neuropathies.

Sitao Yin
Post-Doctoral Fellow

Research Project: I am interested in how post-transcriptional methylation to cytosine contributes to RNA structure and function.

Ryuichi Takase
Post-Doctoral Fellow

Research Project: I am interested in understanding how post-transcriptional methylation to adenine and guanine contributes to RNA structure and function.

Meixia Li
Exchange Student, Huazhong University, China

Research Project: I am interested in studying tRNA methylation and tRNA aminoacylation and the role of these in human health and disease.

Veda Nambi
Undergraduate Study, Bryn Mawr College

Research Project: I am interested in understanding how arginyl-tRNA transferase selects its tRNA substrate.

Ryuma Matsubara

Research Project: I am interested in the genetic network of tRNA methylation in bacteria.