Hou Research

Contact

Position: Professor

233 South 10th Street
BLSB 220
Philadelphia, PA 19107

Contact Number(s):

Our Team

Howard Gamper
Research Assistant Professor

Research Project: I am interested in understanding both programmed and non-programmed tRNA frameshift on the ribosome at the molecular and kinetic levels.

Thomas Christian
Post-Doctoral Fellow

Research Project: I am interested in understanding the molecular and structural mechanisms of tRNA methyltransferases. I would like to determine how specific methyltransferases recognize their tRNA targets and to explore strategies that these enzymes catalyze methyl transfer.

Isao Masuda
Post-Doctoral Fellow

Research Project: I am interested in the mechanism of translational frameshifting, a non-standard phenomenon in decoding genetic codes into proteins. I am going to examine how the tRNAs and ribosomes are involved in frameshifting using both molecular biological and biochemical.

Kevin Donaldson
Masters Student

Research Project: I am interested in how pathogenic mutations in aminoacyl-tRNA synthetases are associated with peripheral neuropathies.

Sitao Yin
Post-Doctoral Fellow

Research Project: I am interested in how post-transcriptional methylation to cytosine contributes to RNA structure and function.

Ryuichi Takase
Post-Doctoral Fellow

Research Project: I am interested in understanding how post-transcriptional methylation to adenine and guanine contributes to RNA structure and function.

Meixia Li
Exchange Student, Huazhong University, China

Research Project: I am interested in studying tRNA methylation and tRNA aminoacylation and the role of these in human health and disease.

Veda Nambi
Undergraduate Study, Bryn Mawr College

Research Project: I am interested in understanding how arginyl-tRNA transferase selects its tRNA substrate.

Ryuma Matsubara

Research Project: I am interested in the genetic network of tRNA methylation in bacteria.

Sunita Maharjen

Research Project: I am interested in mitochondrial biology associated with tRNA mutations and neurodegenerative disease.

Past Team Members

Summer, 2014

  • Angela Chang (University of Pennsylvania)
  • Albert Chang (Radnor High School)

Summer, 2013

  • Jacob Peacock (Harvey Mudd College)
  • David McGuigan III (McGill University)
  • Angela Chang (Radnor High School)
  • Albert Chang (Radnor High School)

Summer, 2012

  • Jacob R. Peacock (Harvey Mudd College)
  • Angela Y. Chang (Radnor High School)
  • Albert J. Chang (Radnor High School)

Summer, 2011

  • Angela Y. Chang (Radnor High School)
  • Aijingwen Li (Bryn Mawr College)
  • Hazal Yilmaz (Sabanci University, Turkey)
  • Lena Ma (Lehigh University)

Summer, 2010

  • Angela Chang (Radnor High School)
  • Lena Ma (Hallahan High School)

Summer, 2009

  • Lena Ma (Hallahan High School)
  • Suhavi Tucker (Haverford College)

Summer, 2008

  • Lena Ma (Hallahan High School)

Summer, 2007

  • Danielle Gunter-Ward (Delaware State University)

Summer, 2004

  • Lindsey Ingerman (Colgate University)

Summer, 2003

  • Lindsey Ingerman (Colgate U)

Summer, 2000

  • Melissa Shive (Chadwick High School)
  • Genessa Doring (UCLA)

Summer, 1999

  • Remyt Florentino (Lawrence High School)
  • Jesse Chang (Penn State U)

Summer, 1998

  • Remyt Florentino (Lawrence High School)
  • Elise Carpenter (Bryn Mawr College)
  • Jennifer Zruski (Bryn Mawr College)

Summer, 1997

  • Remyt Florentino (Lawrence High School)

Summer, 1996

  • Emily Chu (Yale U)