Name: Ya-Ming Hou, PhD
Position: Professor

233 South 10th Street
BLSB 220
Philadelphia, PA 19107

Telephone: 215-503-4480

Recent Publications

tRNA methylation: An unexpected link to bacterial resistance and persistence to antibiotics and beyond

A label-free assay for aminoacylation of tRNA

A Mitochondrial tRNA Mutation Causes Axonal CMT in a Large Venezuelan Family

Mg2+-Dependent Methyl Transfer by a Knotted Protein: A Molecular Dynamics Simulation and Quantum Mechanics Study

tRNAArg-Derived Fragments Can Serve as Arginine Donors for Protein Arginylation

Deacetylation of HSD17B10 by SIRT3 regulates cell growth and cell resistance under oxidative and starvation stresses

Allele-specific RNA interference prevents neuropathy in Charcot-Marie-Tooth disease type 2D mouse models

How to Untie a Protein Knot

Erratum: tRNA Methylation Is a Global Determinant of Bacterial Multi-drug Resistance (Cell Systems (2019)8(4)(302–314.e8), (S240547121930078X), (10.1016/j.cels.2019.03.008))

tRNA Methylation Is a Global Determinant of Bacterial Multi-drug Resistance

Loss-of-function mutations in Lysyl-tRNA synthetase cause various leukoencephalopathy phenotypes

Cysteinyl-tRNA Synthetase Mutations Cause a Multi-System, Recessive Disease That Includes Microcephaly, Developmental Delay, and Brittle Hair and Nails

Codon-specific translation by m1G37 methylation of tRNA

Erratum to: The selective tRNA aminoacylation mechanism based on a single G•U pair (Nature, (2014), 510, 7506, (507-511), 10.1038/nature13440)

TRNA 3-amino-tailing for stable amino acid attachment

Hypermorphic and hypomorphic AARS alleles in patients with CMT2N expand clinical and molecular heterogeneities

Stabilization of Cyclin-Dependent Kinase 4 by Methionyl-tRNA Synthetase in p16INK4a-Negative Cancer

Selective terminal methylation of a tRNA wobble base

Compound heterozygosity for loss-of-function GARS variants results in a multisystem developmental syndrome that includes severe growth retardation

Effect of Nascent Peptide Steric Bulk on Elongation Kinetics in the Ribosome Exit Tunnel

A genetically encoded fluorescent tRNA is active in live-cell protein synthesis

TrmD: A Methyl Transferase for tRNA Methylation With m1G37

Transcription-Translation coupling: Direct interactions of RNA polymerase with ribosomes and ribosomal subunits

Mg2+ regulates transcription of mgtA in Salmonella Typhimurium via translation of proline codons during synthesis of the MgtL peptide

Initiator tRNA genes template the 3' CCA end at high frequencies in bacteria