2020

1. Fay AJ, Garcia Y, Margeta M, Maharjan S, Jürgensen C, Briceño J, Garcia M, Yin S, Bassaganyas L, McMahon T, Hou YM, Fu YH, Ptáček LJ.Ann. A Mitochondrial tRNA Mutation Causes Axonal CMT in a Large Venezuelan Family. Neurol. 2020 Jul 26. doi: 10.1002/ana.25854. Online ahead of print. PMID: 32715519
2. Luo J, Liu L, Chen S, Yu M, Ge C, Ren M, Liu B, Yang X, Christian T, Hou YM, Zou J, Zhu W. (2020) Deacetylation of HSD17B10 by SIRT3 regulates cell growth and cell resistance under stress. Cell Death and Disease 11, 563. PMID: 32703935
3. Avcilar-Kucukgoze I, Gamper H, Polte C, Ignatova Z, Kraetzner R, Shtutman M, Hou YM, Dong DW, Kashina A. tRNAArg-Derived Fragments Can Serve as Arginine Donors for Protein Arginylation. Cell Chem Biol. 2020 Jun 11:S2451-9456(20)30190-2. doi: 10.1016/j.chembiol.2020.05.013. Online ahead of print. PMID: 32553119
4. Hou YM, Masuda I, Foster LJ. tRNA methylation: An unexpected link to bacterial resistance and persistence to antibiotics and beyond. Wiley Interdiscip Rev RNA. 2020 Jun 13:e1608. doi: 10.1002/wrna.1609. Online ahead of print. PMID: 32533808 Review.

2019

1. Morelli, KH, Griffin, LB, Pyne, NK, Wallace, LM, Fowler, AM, Oprescu, SN, Takase, R, Wei, N, Meyer-Schuman, R, Mellacheruvau, D, Kitzman, JO, Kocen, SG, Lupski, JR, Nesvizhskii, A, Mancias, P, Butler, I, Yang, XL, Hou, YM, Antonellis, A, Harper, SQ, Burgress, RW. (2019) Allele-specific RNA interference: Precision gene therapy for dominant inherited neuropathy. J. Clinical Investigation 129: 5568-5583. PMID: 31557132; PMCID:PMC6877339. 
2. Yin S, Dhital B, Hou YM. How to Untie a Protein Knot. Structure, 2019.
3. Kuo ME, Theil AF, Kievit A, Malicdan MC, Introne WJ, Christian T, Verheijen FW, Smith DEC, Mendes MI, Hussaarts-Odijk L, van der Meijden E, van Slegtenhorst M, Wilke M, Vermeulen W, Raams A, Groden C, Shimada S, Meyer-Schuman R, Hou YM, Gahl WA, Antonellis A, Salomons GS, Mancini GMS. Cysteinyl-tRNA Synthetase Mutations Cause a Multi-System, Recessive Disease That Includes Microcephaly, Developmental Delay, and Brittle Hair and Nails. Am J Hum Genet. 7 March 2019.
4. Masuda I, Matsubara R, Christian T, Rojas ER, Yadavalli SS, Zhang L, Goulian M, Foster L, Huang KC, Hou YM. tRNA Methylation Is a Global Determinant of Bacterial Multi-drug Resistance. Cell Systems 10 April 2019.
5. Sun C, Song J, Jiang Y, Zhao C, Lu J, Li Y, Wang Y, Gao M, Xi J, Luo S, Li M, Donaldson K, Oprescu SN, Slavin TP, Lee S, Magoulas PL, Lewis AM, Emrick L, Lalani SR, Niu Z, Landsverk ML, Walkiewicz M, Person RE, Mei H, Rosenfeld JA, Yang Y, Antonellis A, Hou YM, Lin J, Zhang VW. Loss-of-function mutations in Lysyl-tRNA synthetase cause various leukoencephalopathy phenotypes. Neurology Genetics. April 2019.
6. Hou YM, Masuda I, Gamper H. (2019) Codon-Specific Translation by m1G37 Methylation of tRNA. Front. Genet. 10 January 2019

2018

1. Masuda, I, Takase, R, Matsubara, R, Paulines, MJ, Gamper, H, Limbach, PA, Hou, YM. (2018) Selective terminal methylation of a tRNA wobble base. Nucleic Acids Res, 46 (7):e37.

2. Weterman, MAJ, Kuo, M, Kenter, SB, Gordillo, S, Karjosukarso, D, Takase, R, Bronk, M, Oprescu, S, de Wissel, M, van Ruissen, F, Breuning, M, Hou, YM, de Visser, M, Antonellis, A, Baas, F. (2018) Hypermorphic and hypomorphic AARS alleles in patients with CMT2N expands clinical and molecular heterogeneities. Human Molecular Genetics, in press.

3. Gamper, H, Hou, YM. (2018) tRNA 3'-amino-tailing for stable amino acid attachment. RNA.

4. Kwon NH, Lee JY, Ryu YL, Kim C, Kong J, Oh S, Kim SH, Ahn SG, Jeong J, Kim HK, Kim JH, Han DY, Park MC, Takase R, Masuda I, Hou YM, Jang SI, Chang YS, Lee DK, Guo M, Kang BS, Wang MW, Basappa B, Lee JH, Kim S.  (2018) Stabilization of cyclin dependent kinase 4 by methionyl-tRNA synthetase in p16INK4a-negative cancer. ACS Pharmacology & Translational Science, 1, 21-31.

2017

1. Fan H, Conn AB, Williams PB, Diggs S, Hahm J, Gamper HB Jr, Hou YM, O'Leary SE, Wang Y, Blaha GM. Transcription-translation coupling: direct interactions of RNA polymerase with ribosomes and ribosomal subunits. Nucleic Acids Res. 2017 Nov.

2. Oprescu SN, Chepa-Lotrea X, Takase R, Golas G, Markello TC, Adams DR, Toro C, Gropman AL, Hou YM, Malicdan MCV, Gahl WA, Tifft CJ, Antonellis A. Compound heterozygosity for loss-of-function GARS variants results in a multisystem developmental syndrome that includes severe growth retardation. Hum Mutat. 2017 Oct.

3. Hou YM, Matsubara R, Takase R, Masuda I, Sulkowska JI. TrmD: A Methyl Transferase for tRNA Methylation With m1G37. Enzymes. 41:89-115. 2017.

4. Po P, Delaney E, Gamper H, Szantai-Kis DM, Speight L, Tu L, Kosolapov A, Petersson EJ, Hou YM, Deutsch C. Effect of Nascent Peptide Steric Bulk on Elongation Kinetics in the Ribosome Exit Tunnel. J Bol Miol. 429(12):1873-1888. Jun16 2017.

5. Masuda I, Igarashi T, Sakaguchi R, Nitharwal RG, Takase R, Han KY, Leslie BJ, Liu C, Gamper H, Ha T, Sanyal S, Hou YM. A genetically encoded fluorescent tRNA is active in live-cell protein synthesis. Nucleic Acids Res. Apr 20, 2017

2016

1. Gall AR, Datsenko KA, Figueroa-Bossi N, Bossi L, Masuda I, Hou YM, Csonka LN. Mg2+ regulates transcription of mgtA in Salmonella Typhimurium via translation of proline codons during synthesis of the MgtL peptide. Proc Natl Acad Sci USA. Dec 27 2016.
2. Ardell DH, Hou YM. Initiator tRNA genes template the 3' CCA end at high frequencies in bacteria. BMC Genomics. 8 Dec 2016
3. Sakaguchi R, Hou YM. (2016) タンパク質の結び目構造からのシグナルによるtRNAのメチル化修飾. DOI:10.7875/first.author.2016.097.. First Author's
4. Christian T, Sakaguchi R, Perlinska AP, Lahoud G, Ito T, Taylor EA, Yokoyama S, Sulkowska JI, Hou YM. Methyl transfer by substrate signaling from a knotted protein fold.. Nat Struct Mol Biol. Aug 29, 2016
5. Liu C, Stonestrom AJ, Christian T, Yong J, Takase R, Hou YM, Yang X. Molecular Basis and Consequences of the Cytochrome c-tRNA Interaction.. J Biol Chem, 291, 10426-36. May 6, 2016
6. Falk MJ, Gai X, Shigematsu M, Vilardo E, Takase R, McCormick E, Christian T, Place E, Pierce EA, Consugar M, Gamper HB, Rossmanith W, Hou YM. A novel HSD17B10 mutation impairing the activities of the mitochondrial RNase P complex causes X-linked intractable epilepsy and neurodevelopmental regression.. RNA Biol, 13, 477-85 . May 3, 2016

1. Ito, T, Masuda, I, Yoshida, K, Goto-Ito, S, Suh, SW, Hou, YM, Yokoyama, S. Structural mechanism of site-specific RNA modification by the bacterial tRNA(m1G37)-methyltransferase TrmD. Proc Natl Acad Sci, 112, E4197-204. Aug 4 2015

2. Gamper, H, Masuda, I, Frenkel-Morgenstern, M, Hou, YM. The UGG isoacceptor of tRNAPro is naturally prone to frameshifts. Int J. Mol Sci. 16, 14866-14883. Jul 1, 2015

3. Hou, YM, Gamper, H, Yang, W. (2015) Post-transcriptional modifications of tRNA – A response to the genetic code degeneracy. RNA 21, 642-644. Apr 2015

4. Hou, YM, Masuda, I. (2015) Kinetic analysis of tRNA methyltransferases. Methods in Enzymology. Edited by Chuan He, 560, 91-116.

5. Gamper HB, Masuda I, Frenkel-Morgenstern M, Hou YM, Maintenance of protein synthesis reading frame by EF-P and m1G37-tRNAAm J Human Benetics96(4):675-81. doi: 10.1016, April2, 2015

6. Ya-Ming Hou et al., Loss-of-Function Alanyl-tRNA Synthetase Mutations Cause an Autosomal-Recessive Early-Onset Epileptic Encephalopathy with Persistent Myelination DefectAm J Human Genetics96(4):675-81. doi: 10.1016, April2, 2015

1. Akesh Sinha, Caroline Köhrer, Michael H. W. Weber, Isao Masuda, Vamsi K. Mootha, Ya-Ming Hou, and Uttam L. RajBhandary, Biochemical characterization of pathogenic mutations in human mitochondrial methionyl-tRNA formyltransferaseJ. Biol. Chem289(47):32729-41. doi: 10.10742

2. Griffin LB, Sakaguchi R, McGuigan D, Gonzalez MA, Searby C, Züchner S, Hou YM, Antonellis A., (November 2014) Impaired Function is a Common Feature of Neuropathy-Associated Glycyl-tRNA Synthetase MutationsHuman Mutation35(11):1363-71. doi: 10.1002

3. Sakaguchi R, Lahoud G, Christian T, Gamper H, Hou YM., (October 2014) A Divalent Metal Ion-Dependent N(1)-Methyl Transfer to G37-tRNA.J. Chem Biol.21(10):1351-60. doi: 10.1016

4. Oscar Vargas-Rodriguez and Karin Musier-Forsyth, (June 2014) Wobble puts RNA on targetNature News & Views. 480|Nature|Vol 510|26 June 2014.

5. Masahiro Naganuma, Shun-ichi Sekine1, Yeeting Esther Chong, Min Guo, Xiang-Lei Yang, Howard Gamper, Ya-Ming Hou, Paul Schimmel & Shigeyuki Yokoyama1, (June 2014) The selective tRNA aminoacylation mechanism based on a single G.U pairNature. doi:10.1038.

6. James S. PHAM, Reiko SAKAGUCHI, Lee M. YEOH, Nilushi S. DE SILVA, Geoffrey I. MCFADDEN‡, Ya-Ming HOU and Stuart A. RALPH (2014) A dual-targeted aminoacyl-tRNA synthetase in Plasmodium falciparum charges cytosolic and apicoplast tRNACys.Biochem J. 458: 512-523.

7. Jacob R. Peacock, Ryan R. Walvoord, Angela Y. Chang, et al. (2014) Amino acid-dependent stability of the acyl linkage in aminoacyl-tRNA.RNA 20: 758-764.

1. Annia Rodriguez-Hernandez, Jessica L. Spears, Kirk W. Gaston, Patrick A. Limbach, Howard Gamper, Ya-Ming Hou, Rob Kaiser, Paul F. Agris, John J. Perona, (2013) Structural and Mechanistic Basis for Enhanced Translational Efficiency by 2-Thiouridine at the tRNA Anticodon Wobble Position.J. Mol. Biol. 425(20):3888-3906.

2. Isao Masuda, Reiko Sakaguchi, Cuiping Liu, Howard Gamper, Ya-Ming Hou, (2013) The Temperature Sensitivity of a Mutation in the Essential tRNA Modification Enzyme tRNA Methyltransferase D (TrmD).JBC. 288(40):28987-28996

3. Thomas Christian, Howard Gamper, Ya-Ming Hou, (2013) Conservation of structure and mechanism by Trm5 enzymes.RNA. 19(9):1192-9. doi: 10.1261/rna.039503.113.

4. Anna Ochi, Koki Makabe, Ryota Yamagami, Akira Hirata, Reiko Sakaguchi, Ya-Ming Hou, Kazunori Watanabe, Osamu Nureki, Kunihiro Kuwajima, Hiroyuki Hori,(2013) The Catalytic Domain of Topological Knot tRNA Methyltransferase (TrmH) Discriminates between Substrate tRNA and Nonsubstrate tRNA via an Induced-fit Process.J. Biol. Chem. 288:25562-25574. doi: 10.1074/jbc.M113.485128

5. Ya-Ming Hou, Xiaolu Yang (2013) Regulation of Cell Death by Transfer RNA.Antioxidants & Redox Signaling. DOI: 10.1089/ars.2012.5171

1. Reiko Sakaguchi, Anders Giessing, Qing Dai, Georges Lahoud, Zita Liutkeviciute, Saulius Klimasauskas, Joseph Piccirilli, Finn Kirpekar, Ya-Ming Hou (2012) Recognition of guanosine by dissimilar tRNA methyltransferases. RNA. 18: 1687-1701

2. Frenkel-Morgenstern M, Danon T, Christian T, Igarashi I, Cohen L, Hou YM, Jensen LJ. (2012) Genes adopt non-optimal codon usage to generate cell cycle-dependent oscillations in protein levels.Molecular Systems Biology. 8:572.

3. Liu C, Sanders JM, Pascal JM, Hou YM. (2012) Adaptation to tRNA acceptor stem structure by flexible adjustment in the catalytic domain of class I tRNA synthetases.RNA. 18(2):213-21.

4. McLaughlin HM, Sakaguchi R, Giblin W; NIH Intramural Sequencing Center, Wilson TE, Biesecker L, Lupski JR, Talbot K, Vance JM, Züchner S, Lee YC, Kennerson M, Hou YM, Nicholson G, Antonellis A. (2012) A Recurrent loss-of-function alanyl-tRNA synthetase (AARS ) mutation in patients with charcot-marie-tooth disease type 2N (CMT2N).Human Mutation. 33(1):244-53.

1. Silver HR., Nissley JA., Reed SH., Hou YM., Johnson ES. (2011) A role for SUMO in nucleotide excision repair. DNA Repair. 10(12):1243-51

2. Takao I., Liu C., Morinaga H., Kim S., Hou YM. (2011) Pyrophosphorolysis of CCA Additions: Implication for Fidelity. J. Mol. Bio. 414(1):28-43

3. Ghosh A., Sakaguchi R., Liu C., Vishveshwara S., Hou YM. (2011) Allosteric Communication in Cysteinyl tRNA Synthetase - A network of Direct and Indirect readout.J. Biol. Chem. 286(43):37721-31.

4. Lahoud G, Goto-Ito S, Yoshida KI, Ito T, Yokoyama S, Hou YM. (2011 July) Differentiating analogous tRNA methyltransferases by fragments of the methyl donor.RNA. 17(7):1236-46.

5. Liu C, Gamper H, Liu H, Cooperman BS, Hou YM. (2011) Potential for interdependent development of tRNA determinants for aminoacylation and ribosome decodingNat. Commun.. 2:329 doi: 10.1038/ncomms1331 

1. Christian, T, Lahoud, G, Liu, C, Hoffmann, K, Perona, JJ, Hou, YM. (2010) Mechanism of N-methylation by the tRNA m1G37 methyltransferase Trm5. RNA. 16, 2484-2492.

2. Lahouds, G, Hou, YM. (2010) Biosynthesis: A new (old) way of hijacking tRNA.Nature Chem Biol. 6, 795-796.

3. McLaughlin, HM, Sakaguchi, R, Liu, C, Igarashi, T, Chu, K, Lyer, R, Cruz, P, Cherukuri, PF, Hansen, NF, Mullikin, JC, NISC Comparative Sequencing Program, Biesecker, LG, Wilson, TE, Ionasescu, V, Nicholson, G, Searby, C, Talbot, K, Vance, JM, Zuchner, S, Szigeti, K, Lupski, JR, Hou, YM, Green, ED, Antonellis, A. (2010) Compound heterozygosity for loss-of-function lysyl-tRNA synthetase (KARS) mutations in a patient with peripheral neuropathy.J.Am Hum Genetics 87, 560-566.

4. Mei, Y, Stonestrom, A, Hou, YM, Yang, X. (2010) Apoptotic regulation and transfer RNA.Protein & Cell, 1, 795-801.

5. Christian, T, Lahoud, G, Liu, C, Hou, YM. (2010) Control of catalytic cycle by a pair of analogous tRNA modification enzymes.J. Mol. Biol. 400, 204-217.

6. Hou, YM. (2010) CCA addition to tRNA: Implications for tRNA quality control. IUBMB Life 62, 251-260.

7. Hou, YM, Perona, JJ. (2010) Stereochemical mechanisms of tRNA methyl transferases.FEBS Letters 584, 278-286.

1. Liu, C, Betteridge, T, Hou, YM. (2009) Fluorophore labeling to monitor tRNA dynamics.Methods in Enzymology 469 (Editor Herschlag, D, academic press), 69-93.

2. Kim, S, Liu, CP, Halkidis, K, Gamper, H, Hou, YM. (2009) Distinct kinetic determinants for the stepwise CCA addition to tRNA.RNA 15, 1827-1836.

3. Liu, X, Silks, LA, Liu, C, Ollivault-Shiflett, M, Huang, X, Li, J, Wang, Y, Yu, H, Hou, YM, Liu, J, Shen, J. (2009) Incorporation of tellurocysteine into glutathione transferase installs high glutathione peroxidase efficiency. Angew Chem Int Ed Engl 48, 2020-2023.

4. Macauley, SR, Zimmerman, SA, Apolinario, EE, Evilia, C, Hou, YM, Ferry, JG, Sowers, KR. (2009) The archetype gamma-class carbonic anhydrase (Cam) contains iron when synthesized in vivo.Biochemistry 48, 817-819.

1. Lahoud, G, Timoshchuk, V, Levedev, A, Arar, K, Hou, YM, Gamper, H. (2008) Properties of pseudo-complementary DNA substituted with weakly pairing analogs of guanine or cytosine.Nucleic Acids Res 36, 6999-7008.

2. Lahoud, G, Arar, K, Hou, YM, Gamper, H. (2008) RecA mediated DNA strand invasion by pseudo-complementary oligonucleotides.Nucleic Acids Res 36, 6806-6815.

3. Zhang, CM, Liu, C, Christian, T, Gamper, H, Rosenski, J, Pan, D, Randolph, JB, Wickstrom, E, Cooperman, BS, Hou, YM. (2008) Pyrrolo-C as a molecular probe for monitoring conformations of the tRNA 3' end.RNA 14, 2245-2253.

4. Hauenstein, SI, Hou, YM, Perona, JJ. (2008) The homotetrameric phosphoseryl-tRNA synthetase from Methanosarcina mazei exhibits half-of-the-sites activity.J. Biol. Chem. 283, 21997-22006.

5. Pan, D, Zhang, CM, Kirillov, S, Hou, YM, Cooperman, BS. (2008) Perturbation of the tRNA Tertiary Core Differentially Affects Specific Steps of the Elongation Cycle.J. Biol. Chem. 283, 18431-18440.

6. Lahoud, G, Timoshchuk, V, Lebedev, A, de Vega M, Salas, M, Arar, K, Hou, YM, Gamper, H. (2008) Enzymatic synthesis of structure-free DNA with pseudo-complementary properties.Nucleic Acids Res. 36, 3409-3419.

7. Dupasquier, M, Kim, S, Halkidis, K, Gamper, H, Hou, YM. (2008) tRNA integrity is a prerequisite for rapid CCA addition: Implication for quality control.J. Mol. Biol. 379, 579-588.

8. Zhang, CM, Liu, C, Slater, S, Hou, YM. (2008) Aminoacylation of tRNA with phosphoserine for synthesis of Cys-tRNACys.Nature Structural and Molecular Biology 15, 507-514.

9. Francklyn, C, Perona, JJ, First, E, Hou, YM. (2008) Methods for kinetics and thermodynamic analysis of aminoacyl-tRNA synthetases.Methods 44, 100-118.

1. Perona, JJ, Hou, YM. (2007) Indirect readout of tRNA for aminoacylation.Biochemistry 46, 10419-10432. (Selected as an ACS hot article).

2. Christian, T, Hou, YM. (2007) Distinct determinants of tRNA recognition by the TrmD and Trm5 methyl transferases.J. Mol. Biol. 373, 623-632.

3. Betteridge, T, Liu, H, Gamper, H, Kirillov, S, Cooperman, BS, Hou, YM. (2007) Fluorescent labeling of tRNAs for dynamic experiments.RNA 13, 1594-1601.

4. Liu, CP, Gamper, H, Shtivelband, S, Hauenstein, S, Perona, JJ, Hou, YM. (2007) Kinetic quality control of anticodon recognition of a eukaryotic tRNA synthetase.J. Mol. Biol 367, 1063-1078.

1. Zhang, CM, Perona, JJ, Ryu, K, Francklyn, C, Hou, YM. (2006) Distinct kinetic mechanisms of the two classes of aminoacyl-tRNA synthetases.J. Molecular Biology 361, 300-311.

2. Christian T, Evilia, C, Hou, YM. (2006) Catalysis by the second class of tRNA (m1G37) methyl transferase requires a conserved proline.Biochemistry 45, 7463-7473.

3. Gamper, HB, Arar, K, Gewirtz, A, Hou, YM. (2006) Unrestricted hybridization of oligonucleotides to structure-free DNA.Biochemistry 45, 6978-6986.

4. Evilia, C, Hou, YM. (2006) Acquisition of an insertion peptide for efficient aminoacylation by a halophile tRNA synthetase.Biochemistry 45, 6835-6845.

5. Pan, D, Kirillov, S, Zhang, CM, Hou, YM, Cooperman, BS. (2006) Rapid ribosomal translocation depends on the conserved 18-55 base pair in P-site transfer RNA.Nature Structural and Molecular Biology 13, 354-359.

6. Hou, YM, Li, Z, Gamper, H. (2006) Isolation of a site-specifically modified RNA from an unmodified transcript.Nucleic Acids Res. 34, e21.

1. Shitivelband, S, Hou, YM. (2005) Breaking the stereo barrier of amino acid attachment to tRNA by a single nucleotide.J. Mol. Biol, 348, 513-521.

2. Zhang, CM, Hou, YM. (2005) Domain-domain communication for tRNA aminoacylation: The importance of covalent connectivity.Biochemistry 44, 7240-7249.

3. Gamper, HB, Arar, K, Gewirtz, A, Hou, YM. (2005) Unrestricted accessibility of short oligonucleotides to RNA.RNA 11, 1441-1447.

4. Hou, YM, Gu, SQ, Ingerman, L, Zhou, HP. (2005) Metal-ion dependent catalysis and specificity of CCA enzymes: A comparison of two classes.Biochemistry 44, 12849-12859.

1. Hauenstein, S, Zhang, CM, Hou, YM, Perona, JJ. (2004) Shape-selective RNA recognition by cysteinyl-tRNA synthetase.Nature Structural and Molecular Biology 11, 1134-1141. Biochemistry 44, 12849-12859.

2. Ougland, R, Zhang, CM, Liiv, A, Johansen, RF, Seeberg, E, Hou, YM, Remme, J, Falnes, PO. (2004) AlkB restores the biological function of mRNA and tRNA inactivated by chemical methylation.Mol Cell 16, 107-116. Biochemistry 44, 12849-12859.

3. Gamper, HB, Gewirtz, A, Edwards, J, Hou, YM. (2004) Modified bases in RNA reduce secondary structure and enhance hybridization.Biochemistry 43, 10224-10236. Biochemistry 44, 12849-12859.

4. Christian, T, Evilia, C, Williams, S, Hou, YM. (2004) Distinct origins of tRNA(m1G37) methyl transferase.J. Mol. Biol. 339, 707-719.

5. Zhang, CM, Hou, YM. (2004) Synthesis of cysteinyl-tRNACys by a prolyl-tRNA synthetase.RNA Biology 1, 35-41. Biochemistry 44, 12849-12859.

1. Zhang, CM, Perona, JJ, Hou, YM. (2003) Amino acid discrimination by a highly differentiated metal center of an aminoacyl-tRNA synthetase.Biochemistry 42, 10931-10937.

2. Rajanna, C, Wang, J, Zhang, D, Xu, Z, Ali, A, Hou, YM, Karaolis, DKR. (2003) The Vibrio pathogenicity island forms precise extrachromosomal circular excision products. J. Bacteriology 185, 6893-6901.

3. Lipman, RSA, Chen, J, Evilia, C, Vitseva, O, Hou, YM. (2003) Association of an aminoacyl-tRNA synthetase with a metabolic protein in archaea.Biochemistry 42, 7487-96.

4. Evilia, C, Ming, XT, DasSarma, S, Hou, YM. (2003) Aminoacylation of an unusual tRNA from an extreme halophile.RNA 9, 794-801.

5. Zhang, CM, Christian, T, Newberry, KJ, Perona, JJ, Hou, YM. (2003) Zinc mediated amino acid discrimination in cysteinyl-tRNA synthetase.J. Mol. Biol., 327, 911-917.

1. Francklyn, C, Perona, JJ, Putz, J, Hou, YM. (2002) Aminoacyl-tRNA synthetases: versatile players in the changing theater of translation.RNA 8, 1363-1372.

2. Ming, XT, Smith, K, Suga, H, Hou, YM. (2002) Recognition of tRNA backbone for aminoacylation with cysteine: Evolution from E. coli to human.J. Mol. Biol. 318, 1207-1220.

3. Hou, YM. (2002) Base pairing in RNA: Unusual patterns.Encyclopedia of Life Sciences, http://www.els.net. London: Nature Publishing Group.

4. Newberry, KJ, Hou, YM, Perona, JJ. (2002) Structural origins of amino acid selection without editing by cysteinyl-tRNA synthetase. EMBO J. 21, 2778-2787.

5. Seth, M, Thurlow, DL, Hou, YM. (2002) Poly(C) synthesis by class I and class II CCA-adding enzymes.Biochemistry 41, 4521-4532.

6. Lipman, RSA, Beuning, PJ, Musier-Forsyth, Hou, YM. (2002) Amino acid activation of a dual-specificity tRNA synthetase is independent of tRNA.J. Mol. Biol. 316, 421-427.

7. Lipman, RSA, Wang, JL, Sowers, KR, Hou, YM. (2002) Prevention of mis-aminoacylation of a dual-specificity aminoacyl-tRNA synthetase.J. Mol. Biol. 315, 943-949.

1. Tardif, K, Liu, MS, Vitseva, O, Hou, YM, and Horowitz, J. (2001) Misacylation by E. coli valyl-tRNA synthetase: Evidence for two tRNA binding sites.Biochemistry 40, 8118-8125.

2. Burke, B, Lipman, RSA, Shiba, K, Musier-Forsyth, K, Hou, YM. (2001) Divergent adaptation of recognition of tRNAPro by Methanococcus jannaschii prolyl-tRNA synthetase.J. Biol. Chem. 276, 20286-20291.

3. Davidson, E, Caffarella, J, Vitseva, O, Hou, YM, King, MP. (2001) Isolation of two cDNAs encoding functional human cytoplasmic cysteinyl-tRNA synthetase. Biological Chemistry 382, 399-406.

4. Hou, YM, Zhang, XL, Holland, JA, Davis, DR. (2001) An important 2’-OH group for an RNA-protein interaction.Nucleic Acids Res 29, 976-985.

1. Gamper, HB, Hou, YM, Kmiec. (2000) Evidence for a four-strand exchange catalyzed by the recA protein.Biochemistry 39, 15272-15281.

2. Christian, T, Lipman, RSA, Evilia, C, Hou, YM. (2000) Alternative design of a tRNA core for aminoacylation.J. Mol. Biol. 303, 503-514.

3. Hou, YM. (2000) Unusual synthesis by the E. coli CCA-adding enzyme.RNA 6, 1031-1043.

4. Hou, YM, Sundaram, M, Zhang, XL, Holland, JA, Davis, DR. (2000) Recognition of functional groups in an RNA helix by a class I tRNA synthetase.RNA 6, 922-927.

5. Lipman, RSA, Sowers, KR, Hou, YM. (2000) Synthesis of cysteinyl-tRNACys by a genome that lacks the normal cysteine-tRNA synthetase.Biochemistry 39, 7792-7798.

6. Madore, E, Lipman, RSA, Hou, YM, Lapointe J. (2000) Evidence for unfolding of the single-stranded GCCA 3’-end of a tRNA on its aminoacyl-tRNA synthetase from a stacked helical to a fold-back conformation.Biochemistry 39, 6791-6798.

7. Sherlin, LD, Bullock, TL, Newberry, KJ, Lipman, RSA, Hou, YM, Beijer, B, Sproat, BS, Perona, JJ. (2000) Influence of transfer RNA tertiary structure on aminoacylation efficiency by glutaminyl and cysteinyl-tRNA synthetases.J. Mol. Biol. 299, 431-446.

8. Hamann, CS, Hou, YM. (2000) Probing a tRNA core that contributes to aminoacylation.J. Mol. Biol. 295, 777-789.