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Philadelphia, PA 19107
Highlighted Publications
Edmonds, M.D., Boyd, K. L. , Moyo, T., Mitra, R., Duszynski, R., Arrate, M.P., Chen, X., Zhao, Z., Blackwell, T.S., Andl, T., and Eischen, C.M. miR-31 initiates lung tumorigenesis and promotes mutant KRas-driven lung cancer, J. Clinical Invest., 126(1):349-64, 2016.
Adams, C.M., Hiebert, S.W. and Eischen, C.M. Myc induces miRNA-mediated apoptosis in response to HDAC inhibition in hematological malignancies. Cancer Research 76(3):736-48, 2016.
McGirt, L.Y., Jia, P., Baerenwald, D.A., Duszynski, R.J., Dahlman, K.B., Zic, J.A., Zwerner, J.P., Hucks, D., Dave, Z., Zhao, Z., and Eischen, C.M. Whole genome sequencing reveals oncogenic mutations in mycosis fungoides. Blood 126(4):508-19, 2015.
Carrillo, A.M., Bouska, A., Arrate, M.P. and Eischen, C.M.. Mdmx promotes genomic instability independent of p53 and Mdm2. Oncogene 34(7):846-56, 2015.
Grieb, B.C., Gramling, M.W., Arrate, M.P., Chen, X., Beauparlant, S.L., Haines, D.S., Xiao, H., and Eischen, C.M. Oncogenic protein MTBP interacts with MYC to promote tumorigenesis. Cancer Research 74(13):3591-602, 2014.
Recent Publications
C9orf72 poly(PR) mediated neurodegeneration is associated with nucleolar stress
Engaging community members in cancer research: an assessment of an NCI-designated cancer center
CTpathway: a CrossTalk-based pathway enrichment analysis method for cancer research
Stress-triggered hematopoietic stem cell proliferation relies on PrimPol-mediated repriming
MTBP and MYC: A Dynamic Duo in Proliferation, Cancer, and Aging
Mdm4 supports DNA replication in a p53-independent fashion
Targeting BCL-W and BCL-XL as a therapeutic strategy for Hodgkin lymphoma
IL-33 is a cell-intrinsic regulator of fitness during early B cell development
MicroRNA-21 is Required for Hematopoietic Cell Viability After Radiation Exposure
SMARCAL1 and ZrAnB3 protect replication forks from MYC-induced DNA replication stress
The role of inhibition of apoptosis in acute leukemias and myelodysplastic syndrome
Targeting the Bcl-2 family in B cell lymphoma
Targeting of SGK1 by miR-576-3p inhibits lung adenocarcinoma migration and invasion
The proto-oncogene function of Mdm2 in bone
Decoding critical long non-coding RNA in ovarian cancer epithelial-to-mesenchymal transition
Non-Hodgkin and Hodgkin lymphomas select for overexpression of BCLW