Choi Research

Contact

Name: Jason Choi, PhD
Position: Assistant Professor of Medicine, Division of Cardiology
Organization: Department of Medicine

1020 Locust Street
JAH, Room 236
Philadelphia, PA 19107

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Publications

Recent Publications

Perinuclear damage from nuclear envelope deterioration elicits stress responses that contribute to LMNA cardiomyopathy

Med25 Limits Master Regulators That Govern Adipogenesis

Elevated dual specificity protein phosphatase 4 in cardiomyopathy caused by lamin A/C gene mutation is primarily ERK1/2-dependent and its depletion improves cardiac function and survival

Nuclear envelope regulation of signaling cascades

Inhibition of extracellular signal-regulated kinase 1/2 signaling has beneficial effects on skeletal muscle in a mouse model of Emery-Dreifuss muscular dystrophy caused by lamin A/C gene mutation

Reactivation of autophagy ameliorates LMNA cardiomyopathy

Dual specificity phosphatase 4 mediates cardiomyopathy caused by lamin A/C (LMNA) gene mutation

Abnormal p38α mitogen-activated protein kinase signaling in dilated cardiomyopathy caused by lamin A/C gene mutation

Temsirolimus activates autophagy and ameliorates cardiomyopathy caused by lamin A/C gene mutation

Blocking farnesylation of the prelamin A variant in Hutchinson-Gilford progeria syndrome alters the distribution of A-type lamins

Dynamics and molecular interactions of linker of nucleoskeleton and cytoskeleton (LINC) complex proteins

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