Hushan Yang Research
Contact
1025 Walnut Street
Suite 727
Philadelphia, PA 19107
Highlighted Publications
Yang H, Dinney CP, Ye Y, Zhu Y, Grossman HB, Wu X. Evaluation of genetic variants in microRNA-related genes and risk of bladder cancer. Cancer Res. 2008 Apr 1; 68(7):2530-7.
Hildebrandt MA, Yang H, Hung M, Izzo J, Huang M, Lin J, Ajani JA, Wu X. Genetic variations in the PI3K/PTEN/AKT/mTOR pathway are associated with clinical outcomes following chemoradiation for patients with esophageal cancer. J Clin Oncol. 2009 Feb 20; 27(6):857-71.
Mu Z, Wang C, Ye Z, Austin L, Civan J, Hyslop T, Palazzo JP, Jaslow R, Li B, Myers RE, Jiang J, Yang H, Cristofanilli, M. Prospective assessment of the prognostic value of circulating tumor cells and their clusters in patients with advanced-stage breast cancer. Breast Cancer Res Treat. 2015 Dec;154(3):563-71.
Li J, Huang Q, Long X, Zhang J, Huang X, Aa J, Yang H, Chen Z, Xing J. CD147 reprograms fatty acid metabolism in hepatocellular carcinoma cells through Akt/mTOR/SREBP1c and P38/PPARα pathways. J Hepatol. 2015 Dec;63(6):1378-89
Lai Y, Wang C, Civan JM, Palazzo JP, Ye Z, Hyslop T, Lin J, Myers RE, Li B, Jiang B, Sama A, Xing J, Yang H. Effects of Cancer Stage and Treatment Differences on Racial Disparities in Survival from Colon Cancer: A United States Population-Based Study. Gastroenterology. 2016 May;150(5):1135-46.
Wang C, Mu Z, Chervoneva I, Austin L, Ye Z, Rossi G, Palazzo JP, Sun C, Abu-Khalaf M, Myers RE, Zhu Z, Ba Y, Li B, Hou L, Cristofanilli M, Yang H. Longitudinally collected CTCs and CTC-clusters and clinical outcomes of metastatic breast cancer. Breast Cancer Res Treat. 2017 Jan;161(1):83-94.
Wei Q, Ye Z, Zhong X, Li L, Wang C, Myers RE, Palazzo JP, Fortuna D, Yan A, Waldman SA, Chen X, Posey J, Basu-Ballick A, Jiang BH, Hou L, Shu J, Sun J, Xing J, Li B, Yang H. Multiregion whole-exome sequencing of matched primary and metastatic tumors revealed genomic heterogeneity and suggested polyclonal seeding in colorectal cancer metastasis. Ann Oncol. 2017 July; 28: 2135-2141.
Ye Z, Wang C, Wan S, Mu Z, Zhang Z, Abu-Khalaf MM, Fellin FM, Silver DP, Neupane M, Jaslow RJ, Bhattacharya S, Tsangaris TN, Chervoneva I, Berger A, Austin L, Palazzo JP, Myers RE, Pancholy N, Toorkey D, Yao K, Krall M, Li X, Chen X, Fu X, Xing J, Hou L, Wei Q, Li B, Cristofanilli M, Yang H. Association of clinical outcomes in metastatic breast cancer patients with circulating tumor cell and circulating cell-free DNA. Eur J Cancer, 2019 Jan;106:133-143.
Yin C, Li D, Guo X, Cao H, Chen Y, Zhou F, Ge N, Liu Y, Guo S, Zhao Z, Yang H, Xing J. NGS-based profiling reveals a critical contributing role of somatic D-loop mtDNA mutations in HBV-related hepatocarcinogenesis. Ann Oncol. 2019 Mar 18. pii: mdz105. doi: 10.1093.
Bohlius J, Bohlke K, Castelli R, Djulbegovic B, Lustberg MB, Martino M, Mountzios G, Peswani N, Porter L, Tanaka TN, Trifirò G, Yang H, Lazo-Langner A. Management of Cancer-Associated Anemia With Erythropoiesis-Stimulating Agents: ASCO/ASH Clinical Practice Guideline Update. J Clin Oncol. 2019 May;37(15):1336-1351.
Recent Publications
Association between mitochondrial DNA content in leukocytes and colorectal cancer risk
GWAS-identified colorectal cancer susceptibility locus associates with disease prognosis
Genetic variation in microRNA genes and risk of oral premalignant lesions
Genetic variations in PI3K-AKT-mTOR pathway and bladder cancer risk
MicroRNA expression signatures in Barrett's esophagus and esophageal adenocarcinoma
Cyclooxygenase-2 gene polymorphisms reduce the risk of oral premalignant lesions
Single nucleotide polymorphisms of microRNA machinery genes modify the risk of renal cell carcinoma
Genetic susceptibility to renal cell carcinoma: The role of DNA double-strand break repair pathway
Genetic variants in cell cycle control pathway confer susceptibility to bladder cancer