Tomlinson Research
CONTACT
Name:
Ryan Tomlinson, PhD
Position:
- Associate Professor
- Co-director, Cell Biology & Regenerative Medicine PhD Program
Position:
Department of Orthopaedic Surgery and Department of Oral & Maxillofacial Surgery
Organization:
Sidney Kimmel Medical College at Thomas Jefferson University
1015 Walnut Street
Curtis Building, Suite 504
Philadelphia, PA 19107
Email:
Ryan.Tomlinson@jefferson.edu
Contact Number(s):
Publications
Recent Highlighted Publications
- Toll-like receptor 4 signaling in osteoblasts is required for load-induced bone formation in mice
Rajpar I, Kumar G, Fortina P, Tomlinson RE
iScience. 2023 Feb 28;26(4):106304
- The TrkA agonist gambogic amide augments skeletal adaptation to mechanical loading
Fioravanti G, Hua PQ, Tomlinson RE Bone. 2021 Jun;147:115908
- The Role of Nerves in Skeletal Development, Adaptation, and Aging
Tomlinson RE, Christiansen BA, Giannone AA, Genetos DC Frontiers in Endocrinology. 2020 Sep 23
- Local injections of β-NGF accelerates endochondral fracture repair by promoting cartilage to bone conversion
Rivera KO, Russo F, Boileau RM, Tomlinson RE, Miclau T, Marcucio RS, Desai TA, Bahney CS Scientific Reports. 2020 Dec 17
- Fracture repair requires TrkA signaling by skeletal sensory nerves.
Li Z, Meyers CA, Chang L, Lee S, Li Z, Tomlinson RE, Hoke A, Clemens TL, James AW. Journal of Clinical Investigation. 2019 Oct 22
- Naproxen impairs load-induced bone formation, reduces bone toughness, and diminishes woven bone formation following stress fracture in mice.
Park J, Fertala F, Tomlinson RE.
Bone. 2019 Apr 15;124:22-32
- NGF-TrkA signaling in sensory nerves is required for skeletal adaptation to mechanical loads in mice.
Tomlinson RE, Li Z, Li Z, Minichiello L, Riddle RC, Venkatesan A, Clemens TL. Proceedings of the National Academy of Sciences of the United States of America. 2017
- NGF-TrkA signaling by sensory nerves coordinates the vascularization and ossification of developing endochondral bone.
Tomlinson RE, Li Z, Zhang Q, Goh BC, Li Z, Thorek DL, Rajbhandari L, Brushart TM, Minichiello L, Zhou F, Venkatesan A, Clemens TL.
Cell Reports. 2016
Complete List of Publications
Recent Peer-Reviewed Publications
- Medication-related osteonecrosis of the jaw (MRONJ) systemic review: mevalonate pathway mechanisms explored
- Acetaminophen influences musculoskeletal signaling but not adaptations to endurance exercise training
- Regular Nonsteroidal Anti-Inflammatory Drug Use Increases Stress Fracture Risk in the General Population: A Retrospective Case-Control Study
- Cartilage-specific Sirt6 deficiency represses IGF-1 and enhances osteoarthritis severity in mice
- Risk of COVID-19 after natural infection or vaccination
- Toll-like receptor 4 signaling in osteoblasts is required for load-induced bone formation in mice
- Approximating scaffold printability utilizing computational methods
- Optimizing Mineralization of Bioprinted Bone Utilizing Type-2 Fuzzy Systems
- Enhancing precision in bioprinting utilizing fuzzy systems
- Function of peripheral nerves in the development and healing of tendon and bone
- Circulating inflammatory cytokines alter transcriptional activity within fibrotic tissue of Dupuytren's disease patients
- Abcc6 Null Mice—a Model for Mineralization Disorder PXE Shows Vertebral Osteopenia Without Enhanced Intervertebral Disc Calcification With Aging
- Mechanisms of reducing joint stiffness by blocking collagen fibrillogenesis in a rabbit model of posttraumatic arthrofibrosis
- Leveraging advancements in tissue engineering for bioprinting dental tissues
- The TrkA agonist gambogic amide augments skeletal adaptation to mechanical loading
- Emerging evidence that adaptive bone formation inhibition by non-steroidal anti-inflammatory drugs increases stress fracture risk
- Local injections of β-NGF accelerates endochondral fracture repair by promoting cartilage to bone conversion
- Frizzled-4 is required for normal bone acquisition despite compensation by Frizzled-8
- The Role of Nerves in Skeletal Development, Adaptation, and Aging
- Preclinical Single Photon Emission Computed Tomography of Alpha Particle-Emitting Radium-223