- Assistant Professor, Department of Rehabilitation Medicine
- Institute Scientist, Moss Rehabilitation Research Institute
Sensorimotor Learning Laboratory
Moss Rehabilitation Research Institute
50 Township Line Road, Room 306, Elkins Park, PA 19027
Therrien AS, Wolpert DM, Bastian AJ. 2016. Effective reinforcement learning following cerebellar damage requires a balance between exploration and motor noise. Brain, 139: 101-114.
This study was the first to show that cerebellar damage leaves the capacity to leverage reinforcement learning intact, but it can reduce its efficiency.
Therrien AS, Statton MA, Bastian AJ. 2021. Reinforcement signaling can be used to reduce elements of cerebellar reaching ataxia. The Cerebellum, 20: 62-73.
Cerebellar damage impairs motor coordination, causing the movement disorder ataxia. This study was the first to show that reinforcement learning could be leveraged in individuals with cerebellar damage to improve the coordination of their reaching movements.
- Cerebellar Dysfunction in Multiple Sclerosis: Considerations for Research and Rehabilitation Therapy
- Mechanisms of Human Motor Learning Do Not Function Independently
- Is the dynamic gait index a useful outcome to measure balance and ambulation in patients with cerebellar ataxia?
- Non-invasive stimulation of the motor cerebellum has potential cognitive confounds
- Aberrant activity in an intact residual muscle is associated with phantom limb pain in above-knee amputees
- Mechanisms of proprioceptive realignment in human motor learning
- Can the ARAT Be Used to Measure Arm Function in People with Cerebellar Ataxia?
- Reinforcement Signaling Can Be Used to Reduce Elements of Cerebellar Reaching Ataxia
- Interactions between motor exploration and reinforcement learning
- The cerebellum as a movement sensor
- Increasing motor noise impairs reinforcement learning in healthy individuals
- The cerebellum contributes to proprioception during motion
- Proprioceptive Localization Deficits in People With Cerebellar Damage
- Effective Reinforcement learning following cerebellar damage requires a balance between exploration and motor noise
- Cerebellar damage impairs internal predictions for sensory and motor function
- Continuous theta-burst stimulation to primary motor cortex reveals asymmetric compensation for sensory attenuation in bimanual repetitive force production
- Sensory Attenuation of Self-Produced Feedback: The Lombard Effect Revisited
- Continuous theta-burst stimulation to primary motor cortex reduces the overproduction of forces following removal of visual feedback
- Repetitive finger force production in predictable environments
- Timing and visual feedback constraints on repetitive finger force production