Selvakumar Research
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901 Walnut Street
Suite 901
Philadelphia, PA 19107
Highlighted Publications
Selvakumar, P., Owens, T.A., David, J.M., Patrelli, N.J., Christensen, B.C., Lakshmikuttyamma, A., and Rajasekaran, A.K. (2014) Epigenetic silencing of Na,K-ATPase β 1 subunit gene ATP1B1 by methylation in clear cell renal cell carcinoma. Epigenetics 9, 579-586.
Selvakumar, P., Lakshmikuttyamma, A., Shrivastav, A., Das, S.B., Dimmock, J.R., and Sharma, R.K. (2007) Potential Role of N-myristoyltransferase in Cancer. Progress in Lipid Research 46, 1-36.
Selvakumar, P., Lakshmikuttyamma, A., Dimmock, J.R., and Sharma, R.K. (2006) Methionine Aminopeptidase 2 and Cancer. Biochimica et Biophysica Acta-Reviews on Cancer 1765, 148-154.
Selvakumar, P., Windsor, E.S., Bonham, K., and Sharma. R.K. (2006) Expression of N-myristoyltransferase 2 in Human Colon Cancer: Cross-talk Between the Calpain and Caspase System. FEBS Letters 2580, 2021-2026.
Selvakumar, P., Lakshmikuttyamma, A., Lawman, Z., Bonham, K., Dimmock, J.R., and Sharma. R.K. (2004) Expression of Methionine Aminopeptidase 2, N-myristoyltransferase, and N-myristoyltransferase Inhibitor Protein in HT29. Biochemical Biophysical Research Communications 322, 1012-1017.
Selvakumar, P., Lakshmikuttyamma, A., Pasha, M.K., King, M.J., Olson, D.J.H., Mori, S., Ross, A.R.S., Hayashi, K., Dimmock, J.R., and Sharma, R.K. (2004) N-myristoyltransferase Inhibitor Protein is Homologous to Heat Shock Cognate Protein 70. Journal of Cellular Biochemistry 92, 573-578.
Recent Publications
- Tris DBA palladium is an orally available inhibitor of GNAQ mutant uveal melanoma in vivo
- Quercetin regulates β-catenin signaling and reduces the migration of triple negative breast cancer
- Epigenetic silencing of Na,K-ATPase β1 subunit gene ATP1B1 by methylation in clear cell renal cell carcinoma
- Involvement of calpain in colorectal adenocarcinomas (review)
- 3,5-Bis(benzylidene)-1-[4-2-(morpholin-4-yl)ethoxyphenylcarbonyl]-4-piperidone hydrochloride: A lead tumor-specific cytotoxin which induces apoptosis and autophagy
- Molecular cloning and biochemical characterization of bovine retina calcineurin
- Expression and activities of n-myristoyltransferase and calcineurin in normal and inflamed lungs
- 3,5-bis(benzylidene)-4-oxo-1-phosphonopiperidines and related diethyl esters: Potent cytotoxins with multi-drug-resistance reverting properties
- Biochemical characterization of bovine brain myristoyl-CoA:Protein N-myristoyltransferase type 2
- NC2213: A novel methionine aminopeptidase 2 inhibitor in human colon cancer HT29 cells
- Tris (dibenzylideneacetone) dipalladium, a N-myristoyltransferase-1 inhibitor, is effective against melanoma growth in vitro and in vivo
- Myristoyltransferase and calcineurin: Novel molecular therapeutic target for epilepsy
- N-Acyl-3,5-bis(arylidene)-4-piperidones and related compounds which stimulate fyn kinase
- Calmodulin-dependent cyclic nucleotide phosphodiesterase (PDE1) splice variants from bovine cardiac muscle
- Role of calpain and caspase system in the regulation of N-myristoyltransferase in human colon cancer
- Interaction of heat shock protein 70 with calmodulin-dependent cyclic nucleotide phosphodiesterase (PDE 1B1)
- Potential role of N-myristoyltransferase in cancer
- Phosphorylation and dephosphorylation of human myristoyltransferase type 1
- N-Myristoyltransferase 2 expression in human colon cancer: Cross-talk between the calpain and caspase system
- Methionine aminopeptidase 2 and cancer