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Highlighted Publications
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Quaglia, F., Krishn, S.R., Sossey-Alaoui,K., Rana, P., Pluskota, E., Park, P.H., Shields, C.D., Lin, S., McCue, P., Kossenkov, A.V., Wang, Y., Goodrich, D.W., Ku, S.Y., Beltran, H., Kelly, W.K., Corey, E., Klose, M., Bandtlow, C., Liu, Q., Altieri, D.C., Plow, E.F., Languino, L.R. The NOGO receptor NgR2, a novel αVβ3 integrin effector, induces neuroendocrine differentiation in prostate cancer. Scientific Reports (2022); 12(1):18879. DOI: 10.1038/s41598-022-21711-5. PMCID: PMC9640716
Quaglia, F., Krishn, S.R., Sarker, S., Pippa, R., Domingo-Domenech, J., Kumar, G., Fortina, P., Liu, Q., Languino, L.R. Small extracellular vesicles modulated by the αVβ3 integrin induce neuroendocrine differentiation in prostate cancer, Journal of Extracellular Vesicles (2020). PMCID: PMC7448905
Krishn, S.R., Salem, I., Quaglia, F., Naranjo, N., Agarwal, E., McCue, P.A., Weinreb, PH.H., Violette, S.M., Altieri, D.C., Languino, L.R. The αVβ6 integrin in cancer cell-derived small extracellular vesicles enhances angiogenesis, Journal of Extracellular Vesicles (2020). PMCID: PMC7301698
Lu, H., Bowler, N., Harshyne, L., Hooper, D.C., Krishn, S.R., Kurtoglu, S., Fedele, C., Liu, Q., Tang, H., Kossenkov, A.V., Kelly, W.K., Wang, K., Kean, R.B., Weinreb, P.H., Yu, L., Dutta, A., Fortina, P., Ertel, A., Stanczak, M., Forsberg, F., Gabrilovich, D.I., Speicher, D.W., Altieri, D.C. and Languino, L.R. Exosomal ανβ6 Integrin Is Required for Monocyte M2 Polarization in Prostate Cancer. Matrix Biology (2018); 70:20-35. DOI: 10.1016/j.matbio.2018.03.009 [Epub ahead of print]. PMCID: PMC6081240.
Fedele, C., Singh A., Zerlanko, B., Violette, S.M., Iozzo, R. and Languino, L.R. The αvβ6 Integrin is Transferred Intercellularly via Exosomes. J. Biol. Chem. (2015). 290(8):4545-4551. [This article was featured in ASBMB Today 2015 and in Faculty 1000 Jones J and Hopkinson S: F1000Prime Recommendation of [Fedele C et al., J. Biol. Chem. 2015; 290(8):4545-4551. In F1000Prime, 2015]. DOI: 10.1074/jbc.C114.617662. PMCID: PMC4335196.
Additional Recent Peer-Reviewed Publications
- The NOGO receptor NgR2, a novel αVβ3 integrin effector, induces neuroendocrine differentiation in prostate cancer
- STEAP1–4 (Six-Transmembrane Epithelial Antigen of the Prostate 1–4) and Their Clinical Implications for Prostate Cancer
- Ghost mitochondria drive metastasis through adaptive GCN2/Akt therapeutic vulnerability
- Small extracellular vesicle-mediated ITGB6 siRNA delivery downregulates the αVβ6 integrin and inhibits adhesion and migration of recipient prostate cancer cells
- IFIT3 (interferon induced protein with tetratricopeptide repeats 3) modulates STAT1 expression in small extracellular vesicles
- A cancer ubiquitome landscape identifies metabolic reprogramming as target of Parkin tumor suppression
- Differential expression of avß3 and avß6 integrins in prostate cancer progression
- Small Extracellular Vesicle Regulation of Mitochondrial Dynamics Reprograms a Hypoxic Tumor Microenvironment
- Hitting the Bullseye: Are extracellular vesicles on target?
- Announcing the ISEV2020 special achievement award recipients: Andrew Hill and Edit Buzás; and the recipient of the ISEV2020 special education award: Carolina Soekmadji
- Urine Extracellular Vesicle GATA2 mRNA Discriminates Biopsy Result in Men with Suspicion of Prostate Cancer
- Implementation of Germline Testing for Prostate Cancer: Philadelphia Prostate Cancer Consensus Conference 2019
- The mitophagy effector FUNDC1 controls mitochondrial reprogramming and cellular plasticity in cancer cells
- Methods for extracellular vesicle isolation from cancer cells
- Small extracellular vesicles modulated by αVβ3 integrin induce neuroendocrine differentiation in recipient cancer cells
- The αvβ6 integrin in cancer cell-derived small extracellular vesicles enhances angiogenesis
- MFF regulation of mitochondrial cell death is a therapeutic target in cancer
- Identification of monocyte-like precursors of granulocytes in cancer as a mechanism for accumulation of PMN-MDSCs
- Myc-mediated transcriptional regulation of the mitochondrial chaperone TRAP1 controls primary and metastatic tumor growth
- MYC regulation of a mitochondrial trafficking network mediates tumor cell invasion and metastasis