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Highlighted Publications
Please follow the linked titles for full publication.
Verrillo CE, Quaglia F, Shields CD, Lin S, Kossenkov AV, Tang HY, Speicher D, Naranjo NM, Testa A, Kelly WK, Liu Q, Leiby B, Musante L, Sossey-Alaoui K, Dogra N, Chen TY, Altieri DC, Languino LR. Expression of the αVβ3 integrin affects prostate cancer sEV cargo and density and promotes sEV pro-tumorigenic activity in vivo through a GPI-anchored receptor, NgR2. J Extracell Vesicles. 2024 Aug;13(8):e12482. doi: 10.1002/jev2.12482.PMID: 39105261
Naranjo NM, Kennedy A, Testa A, Verrillo CE, Altieri AD, Kean R, Hooper DC, Yu J, Zhao J, Abinader O, Pickles MW, Hawkins A, Kelly WK, Mitra R, Languino LR. Neuroendocrine gene subsets are uniquely dysregulated in prostate adenocarcinoma. Cancer Biol Ther. 2024 Dec 31;25(1):2364433. doi: 10.1080/15384047.2024.2364433. Epub 2024 Jun 26.PMID: 38926911
Krishn, S.R., Salem, I., Quaglia, F., Naranjo, N., Agarwal, E., McCue, P.A., Weinreb, PH.H., Violette, S.M., Altieri, D.C., Languino, L.R. The αVβ6 integrin in cancer cell-derived small extracellular vesicles enhances angiogenesis, Journal of Extracellular Vesicles (2020). PMCID: PMC7301698
Testa A, Quaglia F, Naranjo NM, Verrillo CE, Shields CD, Lin S, Pickles MW, Hamza DF, Von Schalscha T, Cheresh DA, Leiby B, Liu Q, Ding J, Kelly WK, Hooper DC, Corey E, Plow EF, Altieri DC, Languino LR. Targeting the αVβ3/NgR2 pathway in neuroendocrine prostate cancer. Matrix Biol. 2023 Dec;124:49-62. doi: 10.1016/j.matbio.2023.11.003. Epub 2023 Nov 11.PMID: 37956856
Fedele, C., Singh A., Zerlanko, B., Violette, S.M., Iozzo, R. and Languino, L.R. The αvβ6 Integrin is Transferred Intercellularly via Exosomes. J. Biol. Chem. (2015). 290(8):4545-4551. [This article was featured in ASBMB Today 2015 and in Faculty 1000 Jones J and Hopkinson S: F1000Prime Recommendation of [Fedele C et al., J. Biol. Chem. 2015; 290(8):4545-4551. In F1000Prime, 2015]. DOI: 10.1074/jbc.C114.617662. PMCID: PMC4335196.
Additional Recent Peer-Reviewed Publications
- Role of Kindlin 2 in prostate cancer
- Expression of the αVβ3 integrin affects prostate cancer sEV cargo and density and promotes sEV pro-tumorigenic activity in vivo through a GPI-anchored receptor, NgR2
- Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
- Neuroendocrine gene subsets are uniquely dysregulated in prostate adenocarcinoma
- Targeting the αVβ3/NgR2 pathway in neuroendocrine prostate cancer
- Parkin ubiquitination of Kindlin-2 enables mitochondria-associated metastasis suppression
- The NOGO receptor NgR2, a novel αVβ3 integrin effector, induces neuroendocrine differentiation in prostate cancer
- STEAP1–4 (Six-Transmembrane Epithelial Antigen of the Prostate 1–4) and Their Clinical Implications for Prostate Cancer
- Ghost mitochondria drive metastasis through adaptive GCN2/Akt therapeutic vulnerability
- NetrinG1+ Cancer-Associated Fibroblasts Generate Unique Extracellular Vesicles that Support the Survival of Pancreatic Cancer Cells Under Nutritional Stress
- Small extracellular vesicle-mediated ITGB6 siRNA delivery downregulates the αVβ6 integrin and inhibits adhesion and migration of recipient prostate cancer cells
- IFIT3 (interferon induced protein with tetratricopeptide repeats 3) modulates STAT1 expression in small extracellular vesicles
- A cancer ubiquitome landscape identifies metabolic reprogramming as target of Parkin tumor suppression
- Differential expression of avß3 and avß6 integrins in prostate cancer progression
- Small Extracellular Vesicle Regulation of Mitochondrial Dynamics Reprograms a Hypoxic Tumor Microenvironment
- Hitting the Bullseye: Are extracellular vesicles on target?
- Announcing the ISEV2020 special achievement award recipients: Andrew Hill and Edit Buzás; and the recipient of the ISEV2020 special education award: Carolina Soekmadji
- Urine Extracellular Vesicle GATA2 mRNA Discriminates Biopsy Result in Men with Suspicion of Prostate Cancer
- Implementation of Germline Testing for Prostate Cancer: Philadelphia Prostate Cancer Consensus Conference 2019
- The mitophagy effector FUNDC1 controls mitochondrial reprogramming and cellular plasticity in cancer cells