
Lakshmikuttyamma Research
901 Walnut Street
Suite 917
Philadelphia, PA 19107
Highlight Publications
Thangavel K, Lakshmikuttyamma A, Thangavel C, Shoyele SA. CD44-targeted, indocyanine green-paclitaxel-loaded human serum albumin nanoparticles for potential image-guided drug delivery. Colloids Surf B Biointerfaces. 2022, 209(Pt 1):112162. doi: 10.1016/j.colsurfb.2021.112162.
Badgeley A, Anwar H, Modi K, Murphy P, Lakshmikuttyamma A. Effect of probiotics and gut microbiota on anti-cancer drugs: Mechanistic perspectives. Biochim Biophys Acta Rev Cancer. 2021 Jan;1875(1):188494. doi: 10.1016/j.bbcan.2020.188494.
Selvakumar P, Badgeley A, Murphy P, Anwar H, Sharma U, Lawrence K, Lakshmikuttyamma A. Flavonoids and Other Polyphenols Act as Epigenetic Modifiers in Breast Cancer. Nutrients. 2020, 12(3):761. doi: 10.3390/nu12030761.
Modi K, Lawson S, Chen G, Tumuluri D, Rekhtman I, Kurtz M, Brailoiu GC, Chen QH, Lakshmikuttyamma A 1-Chromonyl-5-Imidazolylpentadienone Demonstrates Anti-Cancer Action against TNBC and Exhibits Synergism with Paclitaxel. Int J Mol Sci. 2020, 21(16):5777. doi: 10.3390/ijms21165777.
Kundur S, Prayag A, Selvakumar P, Nguyen H, McKee L, Cruz C, Srinivasan A, Shoyele S, Lakshmikuttyamma A. Synergistic anticancer action of quercetin and curcumin against triple-negative breast cancer cell lines. J Cell Physiol. 2019, 234(7):11103-11118. doi: 10.1002/jcp.27761.
Srinivasan A, Thangavel C, Liu Y, Shoyele S, Den RB, Selvakumar P, Lakshmikuttyamma A. Quercetin regulates β-catenin signaling and reduces the migration of triple negative breast cancer. Mol Carcinog. 2016. (5):743-56. doi: 10.1002/mc.22318. Epub 2015 May 12.
Publications
- Drugs acting on the cerebral and peripheral circulations
- Side effects of antipsychotic agents
- Antipsychotic agents
- CD44-targeted, indocyanine green-paclitaxel-loaded human serum albumin nanoparticles for potential image-guided drug delivery
- Antipsychotic agents
- Effect of probiotics and gut microbiota on anti-cancer drugs: Mechanistic perspectives
- 1-chromonyl-5-imidazolylpentadienone demonstrates anti-cancer action against tnbc and exhibits synergism with paclitaxel
- Flavonoids and other polyphenols act as epigenetic modifiers in breast cancer
- Antipsychotic agents
- Synergistic anticancer action of quercetin and curcumin against triple-negative breast cancer cell lines
- Aptamer-hybrid nanoparticle bioconjugate efficiently delivers miRNA-29b to non-small-cell lung cancer cells and inhibits growth by downregulating essential oncoproteins
- Quercetin regulates β-catenin signaling and reduces the migration of triple negative breast cancer
- Novel targeted siRNA-loaded hybrid nanoparticles: Preparation, characterization and in vitro evaluation
- Drugs of Abuse
- Stable and Efficient Transfection of siRNA for Mutated KRAS Silencing Using Novel Hybrid Nanoparticles
- Epigenetic silencing of Na,K-ATPase β1 subunit gene ATP1B1 by methylation in clear cell renal cell carcinoma
- Investigation of the stability and cellular uptake of self-associated monoclonal antibody (MAb) nanoparticles by non-small lung cancer cells
- Reexpression of epigenetically silenced AML tumor suppressor genes by SUV39H1 inhibition
- Biochemical characterization of bovine brain myristoyl-CoA:Protein N-myristoyltransferase type 2
- NC2213: A novel methionine aminopeptidase 2 inhibitor in human colon cancer HT29 cells