Name: Le Ma, PhD
Position: Associate Professor

233 South 10th Street
BLSB Room 306
Philadelphia, PA 19107

Telephone: 215-503-1108

Highlighted Publications

Gibson D, Tymanskyj S, Yuan R, Leung HC, Lefebvre JL, Sanes JR, Chedotal A, and Ma L (2014) Dendrite self-avoidance requires cell-autonomous Slit/Robo signaling in cerebellar Purkinje cells.  Neuron, 81:1040-56

Xia CH, Nguyen M, Garrison KA, Zhao Z, Wang Z, Sutherland C, and Ma L (2013) CNP/cGMP signaling regulates axon branching and growth by modulating microtubule polymerization.  Developmental Neurobiology,73:673-87. doi: 10.1002/dneu.22078.

Zhao Z and Ma L (2009) Regulation of axonal development by natriuretic peptide hormones.  PNAS, 106(42), 18016-21

Recent Publications

Synaptic dysfunction induced by glycine-alanine dipeptides in C9orf72-ALS/FTD is rescued by SV2 replenishment

MAP7 Prevents Axonal Branch Retraction by Creating a Stable Microtubule Boundary to Rescue Polymerization

Understanding the axonal response to injury by in vivo imaging in the mouse spinal cord: A tale of two branches

MAP7 regulates axon morphogenesis by recruiting kinesin-1 to microtubules and modulating organelle transport

Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels

MAP7 regulates axon collateral branch development in dorsal root ganglion neurons

Dcc Mediates Functional Assembly of Peripheral Auditory Circuits

Slit2 signaling through Robo1 and Robo2 is required for retinal neovascularization

Slit molecules prevent entrance of trunk neural crest cells in developing gut

Dendrite self-avoidance requires cell-autonomous slit/robo signaling in cerebellar purkinje cells

Mutation of Npr2 Leads to Blurred Tonotopic Organization of Central Auditory Circuits in Mice

CNP/cGMP signaling regulates axon branching and growth by modulating microtubule polymerization

Axon Growth and Branching

Slit/Robo signaling mediates spatial positioning of spiral ganglion neurons during development of cochlear innervation

Roundabout Receptors Are Critical for Foregut Separation from the Body Wall

Dystroglycan Organizes Axon Guidance Cue Localization and Axonal Pathfinding

Visualization and Analysis of Microtubule Dynamics Using Dual Color-Coded Display of Plus-End Labels

Slit/Robo Signaling Modulates the Proliferation of Central Nervous System Progenitors

Slits affect the timely migration of neural crest cells via robo receptor

Mosaic analysis of gene function in postnatal mouse brain development by using virus-based cre recombination

Developmental regulation of axon branching in the vertebrate nervous system

Presenilin-dependent receptor processing is required for axon guidance

The development of peripheral cold neural circuits based on TRPM8 expression

Regulation of axonal development by natriuretic peptide hormones

Transient cell-cell interactions in neural circuit formation