Contact
233 S 10th Street
908 BLSB
Philadelphia, PA
Highlighted Publications
Maher CM, Thomas JD, Haas DA, Oyer HM, Tong JY, Kim FJ. Small Molecule Sigma1 Modulator Induces Autophagic Degradation of PD-L1. Molecular Cancer Research. 2018 Feb;16(2):243-255. doi: 10.1158/1541-7786.MCR-17-0166. PMID: 29117944 (*cover article and highlighted in the issue)
Thomas JD, Longen CG, Chen N, Oyer HM, Maher, CM, Salvino JM, Kania B, Ostrander W, Anderson KN, Knudsen KE, Kim FJ. Sigma1 Targeting to Suppress Aberrant Androgen Receptor Signaling in Prostate Cancer. Cancer Research. 2017 Feb 24. pii: canres.1055.2016. PMID: 28235766; PMC5462524
Kim FJ and Maher CM. Sigma1 Pharmacology in the Context of Cancer. Handb Exp Pharmacol. 2017 Sep 5. PubMed PMID: 28871306
Kim FJ. Introduction to Sigma Proteins: Evolution of the Concept of Sigma Receptors. Handb Exp Pharmacol. 2017 Sep 5. PubMed PMID: 28871306
Schrock JM, Spino CM, Longen CG, Stabler SM, Marino JC, Pasternak GW, Kim FJ. Sequential cytoprotective responses to Sigma1 ligand-induced endoplasmic reticulum stress. Mol Pharmacol 84:751-762 (2013). PMCID: PMC3807076; PMC3807076
Recent Publications
Haloperidol and Prostate Cancer Prevention: More Epidemiologic Research Needed
σ
Small-Molecule Sigma1 Modulator Induces Autophagic Degradation of PD-L1
Cloning the sigma
Sigma1 targeting to suppress aberrant androgen receptor signaling in prostate cancer
Introduction to sigma proteins: Evolution of the concept of sigma receptors
Sigma1 pharmacology in the context of cancer
Novel small molecule guanidine Sigma1 inhibitors for advanced prostate cancer
Sequential cytoprotective responses to Sigma1 ligand-induced endoplasmic reticulum stress
Inhibition of tumor cell growth by Sigma1 ligand mediated translational repression