Publications

Contact

Name: Matt Schiewer, PhD
Position: Assistant Professor

233 S 10th Street
BLSB 804
Philadelphia, PA 19107

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Publications

Recent Publications

Master Transcription Factor Reprogramming Unleashes Selective Translation Promoting Castration Resistance and Immune Evasion in Lethal Prostate Cancer

Harnessing transcriptionally driven chromosomal instability adaptation to target therapy-refractory lethal prostate cancer

STEAP1–4 (Six-Transmembrane Epithelial Antigen of the Prostate 1–4) and Their Clinical Implications for Prostate Cancer

A Novel Role for DNA-PK in Metabolism by Regulating Glycolysis in Castration-Resistant Prostate Cancer

Novel Oncogenic Transcription Factor Cooperation in RB-Deficient Cancer

Mutant p53 elicits context-dependent pro-tumorigenic phenotypes

The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair

Rb/e2f1 as a master regulator of cancer cell metabolism in advanced disease

Basic Science and Molecular Genetics of Prostate Cancer Aggressiveness

Targeting the p300/cbp axis in lethal prostate cancer

Implementation of Germline Testing for Prostate Cancer: Philadelphia Prostate Cancer Consensus Conference 2019

USP22 functions as an oncogenic driver in prostate cancer by regulating cell proliferation and DNA repair

Pleiotropic impact of DNA-PK in cancer and implications for therapeutic strategies

Rb1 heterogeneity in advanced metastatic castration-resistant prostate cancer

DNA damage response in prostate cancer

PARP-1 regulates DNA repair factor availability

Patient-derived Models Reveal Impact of the Tumor Microenvironment on Therapeutic Response

MAPK Reliance via acquired CDK4/6 inhibitor resistance in cancer

A patient-derived explant (PDE) model of hormone-dependent cancer

Response and resistance to paradox-breaking BRAF inhibitor in melanomas in vivo and Ex vivo

Detection of activating estrogen receptor gene (ESR1) mutations in single circulating tumor cells

Posttranscriptional regulation of PARG mRNA by HuR facilitates DNA repair and resistance to PARP inhibitors

PARP Inhibitors in Prostate Cancer

Not So Fast: Cultivating miRs as Kinks in the Chain of the Cell Cycle

Cell cycle-coupled expansion of AR activity promotes cancer progression

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